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In Health Care Debate, Small Businesses Are Key
"As they work to overhaul the nation"s healthcare system, President Obama and his congressional allies have pledged to help small-business owners such as Rhonda Ealy and Kelli Glasser," The Los Angeles Times reports. "Both businesswomen desperately want help. But they have strongly divergent views about what Washington should do, reflecting a broader debate about how to relieve the burden on the nation"s roughly 6 million small businesses." Ealy owns a coffee roasting company in Bend, Ore. with 13 employees, she says she "loves a Democratic proposal to create a government-run insurance plan, which she hopes will allow her to get her employees better coverage for less." Glasser, who "makes museum and trade-show exhibits" and has 87 employees, "hates a separate provision in the legislation that would place a new requirement on many businesses to cover their employees."
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DDW 2009 Reveals Advances Being Made In The Treatment Of Hepatitis
Researchers are making great strides in the development of new treatments for hepatitis and in confirming the effectiveness of current treatments, according to several studies presented at Digestive Disease Week® 2009 (DDW®).
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Plexxikon Announces PLX4032 Phase 1 Data Showing Objective Responses In Metastatic Melanoma Patients
Plexxikon Inc. today announced preliminary data from a Phase 1 clinical study investigating PLX4032 (R7204). PLX4032 is a novel, oral and highly selective drug that targets the BRAFV600E cancer-causing mutation that occurs in most melanomas and about eight percent of all solid tumors. In patients whose cancer harbors this mutation and who were treated with therapeutic doses of PLX4032, tumor shrinkage and extended progression-free survival have been observed. Currently, two extension studies are being conducted in mutation-positive melanoma and colorectal cancer patients. Following the initial positive findings announced today, larger clinical trials to support a registration program for product approval are targeted to start later in 2009. Plexxikon and Roche are co-developing PLX4032 under their 2006 license and collaboration agreement.
Diagnostics

AICR Statement: Hot Dogs And Cancer Risk

The American Institute for Cancer Research (AICR) and our landmark 2007 AICR/WCRF expert report, Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective, have been drawn into a controversy over the link between processed meat and cancer risk. A class-action consumer-fraud lawsuit was filed on July 22 against various manufacturers of hot dogs for failing to warn consumers that consumption of hot dogs increases cancer risk. The lawsuit cites evidence from our expert report showing that processed meat consumption is associated with an increased risk of colon cancer. What You Should Know: - Based on the conclusions of our 2007 expert report, AICR recommends limiting consumption of red meat to 18 ounces (cooked) per week, and avoiding processed meat. This is just one of the 10 AICR recommendations for cancer prevention. - AICR does not take a position on the need for warning labels on hot dogs. - AICR is an independent, research-based organization. We fund research on diet and cancer at laboratories, clinics and cancer centers across the country. We also periodically collect and interpret the available data on diet and cancer and issue recommendations for cancer prevention. - AICR is not associated with the Cancer Project, the Physicians Committee for Responsible Medicine or any other advocacy organization. - Our 2007 expert report compiled and analyzed over 7000 studies on all aspects of diet, physical activity, body weight and cancer. - The AICR/WCRF expert panel weighed the evidence on all potential associations and concluded that the link between diets high in red and processed meat and colorectal cancer is convincing. - On the subject of processed meat (hot dogs, cold cuts, ham, etc.) and colon cancer, the collected evidence indicates that every 50 gram serving of processed meat (roughly equivalent to 1 hot dog) eaten per day increases colorectal cancer risk by 21 percent. (Note: this means that people who eat a hot dog every day have a 21 percent higher risk of colorectal cancer than if they never eat hot dogs.) - A 21 percent higher risk is significant and cause for concern; that is why our recommendation is to avoid processed meat. - But, to put that increased risk in context: A regular smoker has a risk of lung cancer that is between 10 and 20 times that of a nonsmoker. In contrast, a person who eats one hot dog every day has a 21 percent higher risk of colorectal cancer - not even two times the risk of someone who never eats hot dogs. - In our literature, AICR does not call on individuals to ban all processed meat from the diet completely. But the evidence does indicate that it makes sense to avoid processed meat when possible. - The AICR/WCRF expert report is a living document. We are continually updating the report"s database with new evidence from emerging studies. An expert panel periodically reviews these new data and determines whether any of AICR"s 10 recommendations need to be changed. - We anticipate that the review of all relevant evidence on colorectal cancer that has appeared since the expert report"s 2007 publication will be completed by the end of this year. At that time, the expert panel will determine whether the recommendation on red and processed meet needs to be changed. - Representatives of the meat industry have attacked our recommendation, citing their own privately commissioned, unpublished meta-analysis. We have reviewed and responded to these criticisms elsewhere. The expert panel stands by its judgment of the evidence, and AICR stands by the report"s transparent, peer-reviewed, comprehensive methodology. The take home message: More people need to know about the healthy everyday choices that can lower risk for cancer. About 1/3 of the most common cancers could be avoided simply by eating a healthy diet, moving more and staying lean. We at AICR work every day to help people make healthy choices; we are committed to changing lives to save lives. American Institute for Cancer Research


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