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Novel Non-Surgical Therapy Dramatically Increases Weight Loss In Obese Patients; Results From Pilot Clinical Study Presented At ASMBS
GI Dynamics, a leader in non-surgical treatments for type 2 diabetes and obesity, today announced results from a pilot clinical study which demonstrated the substantially enhanced weight loss effects of combining the company"s EndoBarrier Gastrointestinal Liner with a new EndoBarrier Flow Restrictor. The EndoBarrier Flow Restrictor provides an adjustable restriction at the outlet of the stomach and is designed to delay gastric emptying, an additional mechanism which adds to the therapeutic effects of the liner. The results were presented today at the 26th annual meeting of the American Society for Metabolic and Bariatric Surgery (ASMBS).
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Breast Cancer Risk Signalled By Wet Ear Wax And Unpleasant Body Odors
If having malodorous armpits (called osmidrosis) and goopy earwax isn"t bad enough, a discovery by Japanese scientists may add a more serious problem for women facing these cosmetic calamities. That"s because they"ve found that a gene responsible for breast cancer causes these physical symptoms. The report describing this finding is featured on the cover of The FASEB Journal"s June 2009 print issue, and should arm physicians with another clue for detecting breast cancer risk.
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New York Times Examines Debate Surrounding Use Of Experimental Treatments In Terminally Ill Patients
Some patient advocates are lobbying to legalize "compassionate use" of experimental drugs for people with terminal illnesses who have exhausted other treatments, prompting a debate about how and when to provide such patients with treatments that could prolong their lives, the New York Times reports. Most insurers do not cover unproven treatments, and physicians have concerns that using experimental treatment could give patients false hope and cause unnecessary pain. Drugmakers are concerned that if there are unfavorable outcomes from providing patients with an unproven treatment, it could hurt the drug"s chances of receiving FDA approval. At the same time, FDA does not want to grant drugs and their makers the opportunity to skip clinical trials. Currently, patients must individually apply to receive treatments through compassionate use (Harmon, New York Times, 5/17).
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Advance In Detecting Melamine-adulterated Food

Researchers in Indiana are reporting an advance toward faster, more sensitive tests for detecting melamine, the substance that killed at least 6 children and sickened 300,000 children in China who drank milk and infant formula adulterated with the substance. The improved tests may ease global concerns about food safety, the researchers say. Their report is scheduled for the May 27 issue of ACS" Journal of Agricultural and Food Chemistry, a bi-weekly publication. In the new study, Lisa Mauer and colleagues note that tests already exist for melamine, which is widely used in plastics. Certain food manufacturers, however, have added melamine to food products marketed for humans and domestic pets to boost apparent protein content. Conventional tests, however, tend to be too slow, insensitive, and too complex for large-scale food screening applications. Researchers say that better detection tests are needed, particularly in the wake of new U.S. Food and Drug Administration (FDA) guidelines limiting melamine in dairy products to 1 part per million (ppm) or less. The scientists describe a trio of promising detection methods based on near- and mid-infrared spectroscopy, analytical techniques that identify a substance based on its chemical fingerprint when exposed to specific kinds of light. In laboratory studies, the scientists used these tests to screen infant formula spiked with different concentrations of melamine. They found that these methods accurately detected the substance at levels as low as 1 ppm, meeting the new FDA detection guidelines. The techniques take as little as 5 minutes to detect melamine and are relatively simple to use, requiring little or no sample preparation. American Chemical Society


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