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'Past Time' To Denounce Tiller Murder, Violence Perpetrated By Some Antiabortion Advocates, Opinion Piece Says
In the wake of the shooting death of Kansas abortion provider George Tiller, columnist Ellen Goodman writes in the Boston Globe that she "can"t help wondering whether rhetoric can justify a crime in the mind of a fanatic." She continues, "Can"t words provide the sort of perverse moral platform that jihadists stand on and the alternate universe in which a "lone nut" can find a home?" Goodman writes that she does not blame Tiller"s death on "everyone who checks a pro-life box on the pollster"s chart," but it is "well past time for the antiabortion movement to denounce those who are in the profession of inflaming passions."Tiller "was a doctor of last resort for many women, especially those women for whom the sonogram did not bring joy but tragic tidings," Goodman writes, adding, "He refused to be cowed. At the very least, he should be buried with truth." In his recent commencement address at the University of Notre Dame, President Obama asked, "As citizens of a vibrant and varied democracy, how do we engage in vigorous debate? How does each of us remain firm in our principles, and fight for what we consider right, without demonizing those with just as strongly held convictions on the other side?" Goodman writes, "One way is for those who truly "denounce the murder" to take on the chorus, the back-up singers, who still provide the doo-wop for the next deranged soloist." She concludes, "You see, this suspect was not such a lone gunman. And no, I am afraid, this was not an isolated incident" (Goodman, Boston Globe, 6/5).
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Rexin-G Controls Tumor Growth And Improves Survival In Chemotherapy-Resistant Sarcoma And Osteosarcoma: Phase I/II And Phase II Studies, ASCO 2009
Epeius Biotechnologies announced the results of two related studies using Rexin-G, a tumor-targeted anti-cancer agent designed to seek-out and destroy metastatic cancers that have spread throughout the body. While Rexin-G is currently approved for the treatment of all solid tumors in the Republic of the Philippines, Epeius Biotech is conducting a series of advanced Phase I/II studies and a Phase II confirmatory trial in the U.S. The Phase I/II study evaluating the safety and efficacy of Rexin-G in chemotherapy-resistant metastatic bone and soft tissue sarcomas (ASCO Annual Meeting 2009, #10513) demonstrated that Rexin-G was well-tolerated with no dose-limiting toxicity. Moreover, Rexin-G exhibited dose-dependent efficacy in terms of tumor control rates, progression-free survival, and overall survival, thus validating both the efficiency of the tumor-targeting technology and the pharmacological mechanisms of action.
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Migraines, Pregnancy And Stroke
For many women who suffer from migraines, pregnancy can be a period of relief from their headaches. Studies have found that preexisting migraines diminish or disappear in 42% to 98% of pregnant women. However, new, persistent, or worsening migraines during pregnancy can signal a serious problem that could result in a stroke. A study published in the March 2009 issue of the British Medical Journal (BMJ) stroke found that migraine was associated with a 17-fold increase in pregnancy-related stroke.
Medical Devices

Dietary Fat, Especially From Red Meat, Dairy, Linked To Pancreatic Cancer

New research from the US that studied the diet and health outcomes of over half a million people suggests that high consumption of dietary fat, especially from red meat and dairy food, is linked to an increased risk of pancreatic cancer. However, some experts suggest that while this is a good study that contributes to our understanding of the disease, it does not prove a link with animal fats per se (it could be some other dietary or lifestyle factor that is common to people who eat lots of animal fat) and that more work is needed before we can be sure. The study was the work of Dr Rachael Z Stolzenberg-Solomon, from the Division of Cancer Epidemiology and Genetics at the National Cancer Institute in Bethesda, Maryland, and colleagues and was published in the advanced access online issue of the Journal of the National Cancer Institute on 26 June 2009. In their background information, Stolzenberg-Solomon and colleagues wrote that they decided to carry out the investigation because up to now research on the link between pancreatic cancer and dietary fat, a risk factor that people can do something about, has been inconclusive. For this prospective study (ie one that follows a certain group over a period of time) the researchers used data from the National Institutes of Health AARP Diet and Health Study, a large US-based group of 308,736 men and 216,737 women aged 50-71 years who filled in a 124-item food frequency questionnaire during 1995 and 1996. The group was then followed for an average of 6.3 years to see what happened to their health, including whether any were diagnosed with pancreatic cancer. After that, the researchers used statistical tools to search for any links between fat consumption, including different types of fat and where it came from, and pancreatic cancer, while taking into account potential confounders like smoking/not smoking, body mass index (BMI), and diabetes. The key results showed that: *865 men and 472 women developed pancreatic cancer (an incident rate 45.0 and 34.5 cases per 100 000 person-years, respectively). *Men and women with the highest total fat consumption were 53 per cent and 23 per cent more likely to receive a pancreatic cancer diagnosis than with men and women with the lowest fat consumption. *There were positive links between pancreatic cancer and intakes of total, saturated and monounsaturated fat overall. *The links were strongest for those whose fat came primarily from red meat and dairy foods. *Those who consumed high levels of saturated fats were 36 per cent more likely to develop pancreatic cancer than those who consumed low levels. The authors wrote that: "We did not observe any consistent association with polyunsaturated or fat from plant food s." They concluded: "In this large prospective cohort with a wide range of intakes, dietary fat of animal origin was associated with increased pancreatic cancer risk." "Altogether, these results suggest a role for animal fat in pancreatic carcinogenesis," they wrote. In an editorial in the same issue of the journal, Drs Brian M. Wolpin from the Dana Farber Cancer Institute in Boston, and Meir J Stampfer from the Harvard School of Public Health, also in Boston, said this was a well-performed study that contributed to our understanding of pancreatic cancer, but there wasn"t enough information to be sure that it was animal fats or fat from red meat that was linked to pancreatic cancer and not something else that is common to people who eat lots of red meat and animal fats. More work would have to be done to show that, but in the meantime "this work has the potential to provide interesting clues to the mechanisms underlying pancreatic tumorigenesis," they wrote. "Dietary Fatty Acids and Pancreatic Cancer in the NIH-AARP Diet and Health Study." Anne C. M. Thiçİbaut , Li Jiao , Debra T. Silverman , Amanda J. Cross , Frances E. Thompson , Amy F. Subar , Albert R. Hollenbeck , Arthur Schatzkin and Rachael Z. Stolzenberg-Solomon. Journal of the National Cancer Institute, Advance Access published on June 26, 2009. DOI 10.1093/jnci/djp168. "Defining Determinants of Pancreatic Cancer Risk: Are We Making Progress?" Brian M. Wolpin and Meir J. Stampfer. Journal of the National Cancer Institute, Advance Access published on June 26, 2009. DOI 10.1093/jnci/djp182. NCI. Written by: Catharine Paddock, PhD Copyright: Medical News Today Not to be reproduced without permission of Medical News Today


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