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Alzheimer, Headache & Co.: Detecting Neurological Illnesses Better And Earlier
The rapid development of modern neuroimaging has made a decisive improvement in the diagnosis of neurological illnesses. As Professor Filippi notes: "Neuroimaging makes new diagnostic tools available with the potential to quantify the extent of CNS injury, to define the nature of the different pathological substrates of the various CNS affections and to assess the functional changes following tissue damage with the ability to limit the clinical consequences of injury."
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AIDS Treatment Activists Push UNAIDS And WHO To Meet Commitments To Reduce HIV In Women And Newborns
In a dramatic meeting today at the UNAIDS headquarters in Geneva, members of the International Treatment Preparedness Coalition (ITPC) and AIDS-Free World met with the leaders and approximately 100 staff members of UNAIDS and WHO to present ITPC"s latest Missing the Target report, Failing Women, Failing Children: HIV, Vertical Transmission and Women"s Health, which identifies the failure of the international community in preventing vertical transmission (also known as prevention of mother-to-child transmission or PMTCT).
News of the day
Proposals May Limit Insurance Choices And Squeeze Some Middle Earners
"President Obama and leading Democrats have stressed that people who like their employer-sponsored insurance would be able to keep it, under a health care overhaul. But they haven"t emphasized the flip side: That people who don"t like their coverage might have to keep it," Kaiser Health News reports. "Under the main health bills being debated in Congress, many people with job-based insurance could find it difficult to impossible to switch to health plans on a new insurance exchange, even if the plans there were cheaper or offered better coverage. The restrictions extend to any government-run plan, which would be offered on the exchange." But "there are a few exceptions: Workers would be allowed to buy insurance through the exchange if their job-based coverage gobbled up too much of their incomes or was too skimpy. Also, under the House proposal, people could get insurance through the exchange if they paid their entire premiums - a cost that would be prohibitive for many workers."
Oncology

Drugs That Fight 2009 H1N1 Influenza A Swine Flu To Be Screened By SRI International

SRI International, an independent, nonprofit research and development organization, has announced that that it will screen a library of well-characterized drugs against the 2009 H1N1 influenza A virus, previously known as "swine flu." The work will be performed under a re contract from the Division of Microbiology and Infectious Diseases (DMID) in the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. There is currently only one class of antiviral drugs, the neuraminidase inhibitors, available to treat this H1N1 infection. Identifying drugs from other chemical and mechanistic classes could provide more effective alternatives to current therapies and make it easier to provide sufficient quantities of drugs to a broad population, should the need arise. The development of new treatments may be expedited by screening drugs that have already well-characterized safety and toxicity profiles. "SRI has expertise in screening new and approved drugs, including the development of novel uses for antibiotics and screening a library of licensed drugs to find compounds that show efficacy against biothreat agents. SRI appreciates the opportunity to apply its knowledge and skills to screening drugs against H1N1 flu and contributing to the overall understanding of the virus," said Amy Shurtleff, Ph.D., a senior virologist in SRI International"s Biosciences Division, who will lead this screening program. Although the number of new 2009 H1N1 influenza A virus cases appears to be slowing worldwide, viruses are unpredictable. In particular, it is not known how this new virus will behave when the seasonal flu season returns this fall and in subsequent years. Scientists are looking at the Southern Hemisphere now, where the flu season will begin soon, for any signs of changes in the H1N1 virus and how humans respond to the infection. SRI has a long and successful history of drug discovery and development, which includes both screening of licensed drugs and finding and studying new chemical and biological therapeutics and vaccines. The virus will be handled in compliance with all guidelines prescribed by the Centers for Disease Control and Prevention (CDC) for handling this strain of influenza. SRI researchers will culture cell lines and study H1N1 virus growth under well-controlled conditions. Next, they will begin testing the first round of drugs. Assuming that some drugs show worthwhile efficacy and potency, SRI will help develop a plan for preclinical and clinical evaluation and regulatory approval. Dina Basin SRI International *See our Map Of H1N1 Outbreaks *See our Mexico Swine Flu Blog


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