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New Oral Agents May Prevent Injury After Radiation Exposure
Researchers from Boston University School of Medicine (BUSM) and collaborators have discovered and analyzed several new compounds, collectively called the ""EUK-400 series,"" which could someday be used to prevent radiation-induced injuries to kidneys, lungs, skin, intestinal tract and brains of radiological terrorism victims. The findings, which appear in the June issue of the Journal of Biological Inorganic Chemistry, describe new agents which can be given orally in pill form, which would more expedient in an emergency situation.
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Can Health Coops Do The Job Of A Public Plan?
"Perhaps the clearest sign yet of the unpredictable nature ofò€¦ an ambitious [health care] policy overhaul is the approach that is suddenly starting to emerge on Capitol Hill as an alternative to a public plan - non-profit, consumer run health insurance cooperatives," Time reports. "Despite no public debate on the issue and scant knowledge about how health cooperatives could be set up - not to mention what they would cost, how many people they could insure and, most importantly, how they could bring down the overall cost of health care - the Senate finance committee appears to have tentatively signed on to the concept; a 10-page outline of a plan drafted by the powerful panel included a proposal for such cooperatives - a little understood concept proposed by" Sen. Kent Conrad, D-N.D. Conrad "has admitted he came up with the idea after giving up hope that bi-partisan legislation was possible if a public health insurance plan was included" (Pickert, 6/22).
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B. Braun Anticipates Becoming First To Deliver FDA Approved 2g Cefazolin
B. Braun Medical Inc. (B. Braun), a leader in infusion therapy and pain management, said today it anticipates U.S. Food and Drug Administration (FDA) approval for 2g Cefazolin for Injection USP and Dextrose Injection USP in B. Braun"s DUPLEX(R) Drug Delivery System.
Diagnostics

High-Grade Prostate Cancer Outcomes Treated With Combination Of Brachytherapy, External Beam Radiotherapy And Hormonal Therapy

UroToday.com - In the online edition of the BJU International, Dr. Richard Stock and colleagues from Mt. Sinai School of Medicine in New York reported on their outcomes using combined radiotherapy approach to men with high-risk prostate cancer (CaP). The study cohort include 181 men with Gleason score 8-10 CaP treated with androgen deprivation therapy (ADT), brachytherapy, and external beam radiotherapy (ERBT) in combination between 1994 and 2006. The study is non-randomized, single institution and retrospective. The ADT was for 3 months followed by brachytherapy and then 2 months later concomitant ADT and ERBT were delivered. The total ADT duration was 9 months. 103Pd was the isotope for all brachytherapy and most men received a dose of 100Gy with 45Gy ERBT. Median follow-up was 65 months and the Phoenix definition of PSA recurrence was used. The overall 8-year actuarial freedom from biochemical failure was 73%. In 36 patients with a biochemical relapse, the median time to PSA failure was 33 months with 53% failing within 3 years. The median PSADT was 2.7 months. Metastatic CaP developed in 22 patients and the 8-year freedom from distant metastases rate was 80%. The cancer-specific survival and overall survival at 8 years were 87% and 79%, respectively. In men experiencing PSA relapse, the 8-year CSS and overall survival were 53% and 51%, respectively. In multivariable analysis, only Gleason score and initial PSA significantly affected the development of biochemical failure. Toxicity from this treatment approach was not reported. Stock RG, Cesaretti JA, Hall SJ, Stone NN BJU Int. 2009 Jun 2. Epub ahead of print. doi:10.1111/j.1464-410X.2009.08661.x Written by UroToday.com Contributing Editor Christopher P. Evans, MD, FACS UroToday - the only urology website with original content written by global urology key opinion leaders actively engaged in clinical practice. To access the latest urology news releases from UroToday, go to: www.urotoday.com Copyright © 2009 - UroToday Copyright: Medical News Today Not to be reproduced without permission of Medical News Today


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