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Gene For Deadly Inherited Lung Disease Identified By Scientists
A rare, deadly developmental disorder of the lungs called alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) that usually kills the infants born with it within the first month of life results from deletions or mutations in the FOXF1 transcription factor gene, said a consortium of researchers led by Baylor College of Medicine (www.bcm.edu) in a report that appears in the American Journal of Human Genetics.
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Children Denied Immunizations At Increased Risk Of Whooping Cough
Children of parents who refuse vaccines are 23 times more likely to get whooping cough compared to fully immunized children, according to a new study led by a vaccine research team at Kaiser Permanente Colorado"s Institute for Health Research.
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Peregrine Pharmaceuticals Reports Progress In Cotara(R) Brain Cancer Clinical Program
Peregrine Pharmaceuticals, Inc. (Nasdaq: PPHM), a clinical stage biopharmaceutical company developing monoclonal antibodies for the treatment of cancer and serious virus infections, provided an update on progress in the company"s clinical program for Cotara(R), a targeted monoclonal antibody-based therapy being tested in a Phase II trial as a potential new treatment for recurrent glioblastoma multiforme (GBM), a deadly form of brain cancer. The company also reported that patient enrollment in the final cohort of a second Cotara GBM trial, a dose confirmation and dosimetry study, is nearing completion and that interim data from this trial has been accepted for an oral presentation at the Society of Nuclear Medicine Annual Meeting to be held June 13-18, 2009.
Public Health

Link Between Vitamin D Insufficiency And Bacterial Vaginosis In Pregnant Women

Bacterial vaginosis (BV) is the most common vaginal infection in US women of childbearing age, and is common in pregnant women. BV occurs when the normal balance of bacteria in the vagina is disrupted and replaced by an overgrowth of certain bacteria. Because having BV puts a woman at increased risk for a variety of complications, such as preterm delivery, there is great interest in understanding how it can be prevented. Vitamin D may play a role in BV because it exerts influence over a number of aspects of the immune system. This hypothesis is circumstantially supported by the fact that BV is far more common in black than white women, and vitamin D status is substantially lower in black than white women. This relation, however, has not been rigorously studied. To assess whether poor vitamin D status may play a role in predisposing a woman to BV, Bodnar and coworkers at the University of Pittsburgh and the Magee-Womens Research Institute studied 469 pregnant women. The results of their investigation are published in the June 2009 issue of the Journal of Nutrition. This prospective epidemiologic study investigated the relation between vitamin D status and BV in 209 white and 260 black women at


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