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Maryland Stem Cell Research Commission Announces 59 Projects For Funding
The Maryland Stem Cell Research Commission (Commission) has completed its evaluation of the 147 applications in response to its three official Requests for Applications (RFAs). The board of directors of the Maryland Technology Development Corporation (TEDCO) reviewed the Commission"s recommendations today and approved 59 projects totaling $18.9 million in funding through the Maryland Stem Cell Research Fund (MSCRF) under the Maryland Stem Cell Research Act of 2006.
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NOVAVAX Achieves Pandemic H1N1 Influenza Production Milestone
Novavax, Inc. (Nasdaq: NVAX) announced it has manufactured a virus-like particle (VLP) vaccine candidate against the H1N1 pandemic influenza virus under current good-manufacturing practices (cGMP) at its new vaccine manufacturing facility in Rockville, MD. This milestone was accomplished in only 11 weeks after receiving the gene sequence for the H1N1 strain from the U.S. Centers for Disease Control. The Company was able to reach this manufacturing goal by employing proprietary, novel production technology which is not dependent on growing influenza virus in eggs. Chicken eggs are used to produce almost all of the world"s influenza vaccine supply. In addition, Novavax has produced essential reagents for measuring vaccine potency. The Company also has plans to produce additional batches of the pandemic H1N1 VLP vaccine to support human clinical studies and stands ready to assist with additional public health needs in the US as well as foreign countries.
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Lyme Disease Is Spreading In Canada, And Physicians Are Crucial In Helping Minimize Its Impact

Lyme disease is emerging in Canada, and is expected to increase with climate change, but effective, enhanced surveillance and clinician awareness will be key to minimizing the impact of the disease, write researchers in a review in CMAJ . Lyme disease is transmitted by ticks which feed on animal or human hosts. It begins with a skin lesion that expands and if untreated, can result in facial palsy, meningitis, cardiac issues and progress to nerve damage (peripheral neuropathy) and inflammation of the brain and spinal cord (encephalomyelitis). Epidemiological understanding about a patient"s likely exposure to ticks is key, as serological testing is insensitive in the early stages of disease but can be useful in the later stages. Current passive surveillance for ticks has identified new endemic areas in Canada but additional methods are needed to identify emerging areas of Lyme disease. Populations of the tick (Ixodes scapularis) are emerging in southern Ontario, Nova Scotia, southeastern Manitoba, New Brunswick and southern Quebec. Tick populations (I. pacificus) are widespread in southern British Columbia, although the prevalence of the Lyme disease agent (Borrelia burgdorferi) in those populations is lower than in the tick spreading in the east. Vigilance by clinicians will help in disease surveillance and in prompt treatment. An important role of surveillance will be to inform the public and physicians about local risks and what to do for prevention and early diagnosis of Lyme disease. "Lyme disease is emerging in Canada, and effective, enhanced surveillance needs to be instigated, and physician awareness of Lyme disease will be crucial to minimizing the impact of the disease," write Dr. Nicholas Ogden from the Public Health Agency of Canada and coauthors. Canadian Medical Association Journal


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