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Could Hormones Explain Gender Differences In Neurological Disease?
Neurological diseases including Parkinson"s, Tourette"s, attention deficit hyperactivity disorder (ADHD), Alzheimer"s, and schizophrenia are all associated with alterations in dopamine-driven function involving the dopamine transporter (DAT). Research published recently in the open access journal BMC Neuroscience suggests that a number of estrogens acting through their receptors affect the DAT, which may explain trends in timing of women"s susceptibility to these diseases.
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Celleron Therapeutics And Astrazeneca Announce Personalised Medicine Collaboration In Cancer For The Development Of AZ's Leading HDAC Inhibitor
Celleron Therapeutics Ltd, the Oxford UK based specialist in the development of individually targeted cancer medicines, has secured exclusive rights to AstraZeneca plc"s lead histone deacetylase (HDAC) inhibitor (AZD 9468), for global development in conjunction with its proprietary "CancerNav" predictive biomarker platform. "CancerNav" specifically identifies those tumours which are most likely to respond to an individual cancer drug, thereby enabling a highly focussed clinical development and commercialisation programme, based on a closely linked diagnostic and therapeutic "personalised medicine" approach.
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What Is Tonsillitis? Who Gets Tonsillitis?
The tonsils are fleshy pieces of lymphatic tissue that rest in the back of the throat above and below the tongue. As part of the immune system, the tonsils help fight infections. However, if bacteria or viruses contaminate the tonsils, the result is an infectious inflammation and swelling of the tonsils - or tonsillitis.
Medical Devices

New Health Snapshots Show States Vary Widely In Providing Quality Health Care

The Agency for Healthcare Research and Quality"s annual release of state-by-state quality data continues to give states mixed reviews for the quality of care they provide. As in previous years, AHRQ"s 2008 State Snapshots show that no state does well or poorly on all quality measures. The U.S. Department of Health and Human Services is also releasing state-by-state reports on the health care status quo. The 2008 State Snapshots provide state-specific health care quality information, including strengths, weaknesses and opportunities for improvement. The state-level information used to create the State Snapshots is drawn from the 2008 National Healthcare Quality Report, which was released in May by HHS Secretary Kathleen Sebelius and contributes to a national portrait of health care quality. "The State Snapshots are an invaluable re for state officials, health care providers and purchasers to help them better understand the extent of health care quality and disparities in their states," said AHRQ Director Carolyn M. Clancy, M.D. "With this information, they can take the necessary steps to improve health care quality and address persistent gaps in access to health care." The 2008 State Snapshots summarize health care quality in three dimensions: type of care (preventive, acute and chronic care), setting of care (hospitals, ambulatory, nursing homes and home health care) and by clinical areas (cancer, diabetes, heart disease, maternal and child health and respiratory disease). The 2008 State Snapshots allow users to explore whether a state has improved or worsened compared with other states in several areas of health care delivery. New features in the 2008 State Snapshots provide more ways to analyze the quality of health care for each state compared with all states, as well as states in the same region. Enhanced features include: -- A new Focus on Asthma section: This section includes state-specific information on the prevalence of adult self-reported asthma rates; potentially preventable hospitalizations for children, adults and the elderly; and potential returns on investment of asthma care quality improvement programs for Medicaid, state employees and privately insured Americans. -- An expanded Focus on Disparities: This section includes state-specific information on disparities in the quality of care compared with the nation overall by looking at care received by various racial/ethnic and socioeconomic groups. This section also includes new information on prevalence of diabetes that includes a U.S. map showing the adult self-reported prevalence of diabetes by state. -- Enhanced Dashboards: The dashboard for each state now contains revised graphics that succinctly display all of the summary measures on health care quality and allow a clear view of the range of each state"s performance. AHRQ"s annual State Snapshots are based on data drawn from more than 30 s, including government surveys, health care facilities and health care organizations AHRQ


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