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Rexin-G Controls Tumor Growth And Improves Survival In Chemotherapy-Resistant Sarcoma And Osteosarcoma: Phase I/II And Phase II Studies, ASCO 2009
Epeius Biotechnologies announced the results of two related studies using Rexin-G, a tumor-targeted anti-cancer agent designed to seek-out and destroy metastatic cancers that have spread throughout the body. While Rexin-G is currently approved for the treatment of all solid tumors in the Republic of the Philippines, Epeius Biotech is conducting a series of advanced Phase I/II studies and a Phase II confirmatory trial in the U.S. The Phase I/II study evaluating the safety and efficacy of Rexin-G in chemotherapy-resistant metastatic bone and soft tissue sarcomas (ASCO Annual Meeting 2009, #10513) demonstrated that Rexin-G was well-tolerated with no dose-limiting toxicity. Moreover, Rexin-G exhibited dose-dependent efficacy in terms of tumor control rates, progression-free survival, and overall survival, thus validating both the efficiency of the tumor-targeting technology and the pharmacological mechanisms of action.
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Cancer Researchers Link DICER1 Gene Mutation To Rare Childhood Cancer
Research published recently in Science Express from the journal Science demonstrates the first definitive link between mutations in the gene DICER1 and cancer. By studying the patterns of DNA from 11 families with an unusual predisposition to the rare childhood lung cancer pleuropulmonary blastoma (PPB) investigators found that children with the cancer carried a mutation in one of their two DICER1 gene copies.
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Budget Bravely Battles Medical Workforce Training And Education Issues
The Australian Medical Students" Association (AMSA) is pleased that a significant proportion of the limited
Endocrinology

Precision Imaging Ultrasound Software For Toshiba's Aplio XG Provides Unprecedented Image Clarity And Resolution

To help leading healthcare institutions increase productivity while improving patient care in diagnostic imaging, Toshiba America Medical Systems, Inc., has introduced Precision Imaging technology available on the Aplio™ XG ultrasound system. Precision Imaging technology acquires ultrasound images of unprecedented clarity and resolution, enabling users to see more clinical detail than ever before. Precision Imaging technology increases productivity and diagnostic confidence by providing more detailed ultrasound images. As a multi-resolution signal processing technology, it not only evaluates images line-by-line, but also includes information from adjacent lines to enhance the amount of information obtained. Traditional ultrasound systems acquire images line-by-line only and do not consider information from adjacent lines. As a Toshiba-exclusive software, Precision Imaging"s ability to capture information from multiple lines improves the definition of the structure, provides more detail and minimizes noise and clutter. This approach enables clinicians to determine if the signal is part of a structure or an anomaly from one line. "Precision Imaging software shows greater definition of structures and reduces noise to produce high quality ultrasound images," explained Dr. Edward G. Grant, M.D., professor and chairman of radiology, USC Medical School, who evaluated the new technology throughout the past two months. "Compared to other ultrasound imaging technologies, Precision Imaging shows better contrast and delineation of lesions, vessels and other objects. It enhances our capability to evaluate difficult to image areas and improves diagnoses." Precision Imaging is beneficial for head-to-toe scanning. It improves the ability to show subtle tissue differences and image small structures better than conventional imaging. It clearly shows contrast boundaries between tissue and lesions, visualizes vessel walls, and enhances true color borders in difficult to image areas. It is useful for imaging breast lesions, superficial regions, small parts, the abdomen, spleen, liver and thyroid. "Toshiba is committed to developing imaging technology that not only improves patient care and safety, but also enhances workflow and productivity," said Girish Hagan, vice president, Marketing, Toshiba. "Precision Imaging does just that. It provides unprecedented ultrasound image clarity and resolution, which enables our customers to view more clinical detail using a single imaging technique, faster and better than before." Precision Imaging is available on the Toshiba Aplio XG. The first deliveries to customers are scheduled for July 2009, with product demonstrations available now. About Toshiba"s Aplio XG Offering the latest advancements in diagnostic performance and operator comfort, the next generation Aplio XG ultrasound system provides several enhancements that improve productivity, increase diagnostic confidence, facilitate connectivity and enhance ergonomics. Upgrade enhancements include new 4D technology, which allows users to acquire volume data sets for subsequent, off-line review. The Aplio XG"s 3D multi-slice view delivers sequential imaging with a presentation format similar to CT and MR. Additionally, slice thickness and the number of images displayed can be selected by the user. A new ergo-optimized control panel and 19ò€³ LCD also have been added to increase user comfort. The Aplio XG also is IHE compliant for improved connectivity and workflow. Toshiba


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