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Ginger Reduces Chemotherapy Nausea, Study
Taking ginger supplements with standard anti-vomiting drugs beforehand can reduce the nausea that often accompanies chemotherapy treatment
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Experts Support National Public Reporting Of Healthcare-Associated Infections
Five organizations representing the nation"s experts in infectious diseases medicine, infection prevention in healthcare settings, and public health and disease prevention announced their support for a provision requiring national reporting of healthcare-associated infection (HAI) rates, which is contained within the healthcare reform bill introduced by leaders of the U.S. House of Representatives.
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Exenatide Once Weekly Provided Superior Glucose Control Compared To Lantus(R) In Head-to-Head DURATION-3 Study
Amylin Pharmaceuticals, Inc. (Nasdaq: AMLN), Eli Lilly and Company (NYSE: LLY) and Alkermes, Inc. (Nasdaq: ALKS) today announced positive results from a study comparing subjects randomized to either exenatide once weekly or Lantus® (insulin glargine). Patients randomized to exenatide once weekly experienced a statistically superior reduction in A1C, a measure of average blood sugar over three months, of 1.5 percentage points from baseline, compared to a reduction of 1.3 percentage points for Lantus after completing 26 weeks of treatment. At the end of the study, patients treated with exenatide once weekly achieved a mean A1C of 6.8 percent compared with a mean A1C of 7.0 percent in those treated with Lantus. Treatment with exenatide once weekly also produced a statistically significant difference in weight, with a mean weight loss of 5.8 pounds at 26 weeks, compared with a mean weight gain of 3.1 pounds for Lantus, a difference of 8.9 pounds between the treatments.
Public Health

The Anatomical Graduated Component Total Knee Replacement

This study examined the 20-year follow-up of the cemented Anatomical Graduated Component total knee replacement carried out between 1983 and 2004. The results showed that the overall survival rate at 20 years was 97.8% with revision of the tibial or femoral component as the endpoint. The survival rate at 20 years of the tibial component was 98.3% and the femoral component was 99.4%. None of the 36 implants at the 20 year follow-up had been revised for polyethylene wear or osteolysis, which may be a reflection of the use of a non-modular, compression-moulded polyethylene implant, since other studies have found polyethylene wear to be a leading cause of failure leading to revision. Therefore, the authors attribute the success of the Anatomical Graduated Component total knee replacement to its relatively unconstrained articular geometry and the durability of a non-modular metal-backed tibial component with compression-moulded polyethylene. Read the full text article. The Journal of Bone and Joint Surgery


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