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Perforomist Inhalation Solution Data Presented At American Thoracic Society Conference
Data from two presentations highlighting the use of Perforomist® (formoterol fumarate) Inhalation Solution in moderate to severe chronic obstructive pulmonary disease (COPD) patients were featured at the International Conference of the American Thoracic Society in San Diego. In one analysis, use of Perforomist Inhalation Solution, when added to maintenance tiotropium, resulted in improved pulmonary function, dyspnea (shortness of breath) and rescue medication use versus treatment with tiotropium alone. In a second study, patient satisfaction increased in those treated with Perforomist Inhalation Solution twice daily compared with ipratropium/albuterol metered-dose inhaler (MDI) four times daily.
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Importance Of 'Moral Values' Replaced By Economy, Health Care For Voters, Washington Post Columnist Says
Since the 2004 election, issues relating to the economic recession and health care have replaced "moral values" as the most important political topics in the U.S., columnist E.J. Dionne writes in a Washington Post opinion piece. He cites a survey released in May by the Pew Research Center that offered respondents the same list of issues that appeared on the 2004 exit poll and found that the importance of moral values had decreased by more than half. Dionne writes that concern over the economy and jobs had more than doubled on the survey, while issues such as health care and education also had "gained substantial ground." According to the survey, "The drop in concern over moral values was particularly sharp among older working-class voters who have been trending Republican for years," Dionne writes.According to Dionne, "Conservative moral values voters have become the heart of the Republican coalition, and if their ranks are shrinking, so is the GOP"s base." He writes that it "is no accident that President Obama takes every opportunity to shift the public debate to issues -- the economy, health care and education -- that the populist conservatives ... find appealing."According to Dionne, "[f]ew recent survey findings are more enlightening about what"s happening in American politics -- and what is likely to happen to the debate over the Supreme Court nomination of Judge Sonia Sotomayor." He adds that it is "striking that while some antiabortion groups issued stinging press releases against Sotomayor, her views on abortion remain a mystery -- to the consternation of abortion-rights supporters." According to Dionne, "Both sides in the abortion debate want to have a confrontation that Sotomayor may not give them the opportunity to stage." He adds that the "vast majority of Americans are not clamoring for this particular battle" (Dionne, Washington Post, 6/1).
News of the day
What Makes An Angry Fly?
A suite of genes that affect aggression in the fruit fly Drosophila melanogaster has been identified. By investigating male flies from a large panel of lines which each carry a mutation in a single gene but are otherwise genetically identical, researchers writing in the open access journal BMC Biology identified particularly angry and particularly placid insects, uncovering 59 mutations in 57 genes that affect aggressive behavior.
Sexual Health

Z-Cube And Yissum Research Development Company Ltd. Sign A Licensing Agreement

Z-Cube Srl, the corporate venture arm of Zambon Company SpA, and Yissum Research Development Company Ltd., the technology transfer company of the Hebrew University of Jerusalem, announced today that they have entered into a license agreement for Z-Cube to develop and commercialize an innovative nanotechnology drug delivery system for the treatment of pain. The technology was invented by Professor Elka Touitou from the Department of Pharmaceutics, Faculty of Medicine, at the Hebrew University of Jerusalem. Under the terms of the agreement, Z-Cube has received the worldwide exclusive right to develop and commercialize the technology for pain applications and will sponsor a research program to be conducted by Prof. Touitou and her group. Z-Cube has also received the right to grant sublicenses. Yissum will receive license fees, milestones and royalty payments. "We are pleased to partner with Z-Cube, a world leader in the commercialization of drug delivery technologies," said Yaacov Michlin, CEO of Yissum. "Our novel drug delivery system has the potential to enable relief of both mild and severe pain quickly and efficiently." The work of Prof. Touitou, a worldwide authority in the drug delivery field, focuses on the design of novel carriers for enhanced drug absorption and efficiency. Two start-up companies have been established and are active in the development of various novel pharmaceutical products that are based on her previously-developed innovative technologies. "This innovative drug delivery system is a powerful tool enabling the development of improved medicines for the treatment of pain," said Lorenzo Pradella, Ph.D., Business and Operational Development Director of Z-Cube. "Patients suffering from pain will benefit from this new approach that promises to generate upgraded and easier to use therapeutics." In 2007, the worldwide market for pain management products (excluding over-the-counter products) was approximately $ 4.2 billion, representing one of the largest pharmaceutical segments. The expectation is that the demand for prescription pain management products will continue to grow due to favorable demographics, increasing incidence of chronic pain conditions, and heightened awareness of physicians for the need to treat pain. Improved pain treatment includes not only the discovery and marketing of new chemical entities, such as pain killers, but also the development of new delivery systems devoted to reducing side effects, increasing safety and improving compliance. Yissum Ltd.


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