Cardiovascular
When doctors are managing care for women with breast cancer, the information available to them profoundly influences the type of care they recommend. Knowing whether a woman"s cancer has metastasized, for instance, directly affects how her doctors will approach treatment -- which may in turn influence the outcome of that treatment.
Nearly three decades after China implemented its one-child policy, the city of Shanghai is planning to encourage young couples to have a second child in an effort to address the country"s aging population and shrinking work force, the New York Times reports. The city"s plan is the most public effort made by the government to counteract a program that is "considered both a tremendous success and a terrible failure," the Times reports. The policy has managed to keep population growth under control but also has led to forced abortions, according to the Times.The country is not abandoning the one-child policy, which applies mostly to residents in urban areas. Rather, the government is allowing more exceptions to the rule, with Shanghai -- where about 22% of its 20 million residents are older than age 60 -- leading the effort. China as a whole faces a similar problem seen in Shanghai, the Times reports. About 8% of the country"s population was older than age 65 in 2006. That figure is expected to increase threefold by 2050 to about 322 million people, or nearly 25% of the population, according to the United Nations.In Friday"s issue of China Daily, Xie Lingli, director of the Shanghai Population and Family Planning Commission, was quoted as saying, "We advocate eligible couples to have two kids because it can help reduce the proportion of the aging people and alleviate a work force shortage in the future." City officials plan to visit homes, pass out leaflets, and offer counseling and financial incentives, the Times reports. Current exceptions to the one-child policy are in place for ethnic minorities and rural residents, who can have a second child if the first child is a girl. Couples made up of two parents who have no siblings have always been allowed to have a second child and are now being encouraged to do so (Barboza, New York Times, 7/24).
"The current debate over government funding for abortion in the health care plan is a reminder of how we have failed poor women," Frances Kissling writes in a Salon opinion piece. According to Kissling, the 32-year-old Hyde Amendment, which prohibits federal funding for abortion services, has played a large role in denying impoverished women access to the procedure. "Restoring those funds has not been a top priority for pro-choice advocates, who sadly concluded that because the public does not care about poor women and is actually hostile to poor women who have sex and become pregnant, it would be futile to put too much capital into reversing Hyde," Kissling writes.However, "we have an opportunity to make amends" by reversing the Hyde Amendment and restoring federal funding for abortion services, according to Kissling. "But the portents are not promising," she writes, adding that a group of "pro-life" Democrats in the House in a recent letter to House Speaker Nancy Pelosi (D-Calif.) "laid down the first major antiabortion challenge to health care reform." In addition, the Obama administration "has refused to rule out including abortion in the health care package, but President Obama is already signaling that the status quo on abortion is likely to endure," Kissling writes."The longer it takes to pass a plan, the more momentum against including coverage for abortion -- and possibly contraception -- will build," Kissling writes, adding that "there is a good chance there will be limits on government funding for abortions in the health care package, if not outright exclusion." A compromise being considered by the House Energy and Commerce Committee would not prohibit or require private insurers offering government plans from covering abortions but would prohibit the use of federal funds to pay for them. "Whether this would result in a reduction of coverage in such plans is unclear, but it is possible," she continues."The timing is critical. The need is great, and growing," Kissling writes, adding, "If abortion services are excluded from the health care reform package, the number of women who will not be able to afford abortions is bound to rise and the number of unwanted children will increase." Kissling concludes, "One hears over and over again that we all agree that the health care system is broken; the status quo is not acceptable. The status quo on coverage for abortion is especially unacceptable" (Kissling, Salon, 7/27).
The Washington Post tells the story of Danny Watt, who drowned in April 2008 after a lifelong struggle with mental health. Watt had a dual diagnosis: a serious mental illness along with abuse of drugs or alcohol.
Researchers may be able to predict future severe cardiac events in patients with known, stable coronary artery disease (CAD) using coronary calcium scoring, according to a study published in the online edition of Radiology.
A new urine test developed with funding from the Wellcome Trust will allow doctors to diagnose Chlamydia infection in men within the hour, improving the ability to successfully treat the infection on the spot and prevent re-transmission.
The assumption that gangs are at the root of gun crime in the UK is overstated, according to a study published in a special issue of Criminology and Criminal Justice, published by SAGE.
Hoag Memorial Hospital Presbyterian announced promising data from a clinical study showing patient-specific cancer vaccines derived from patients" own cancer cells and immune cells were well tolerated and resulted in impressive long-term survival rates in patients with metastatic melanoma whose disease had been minimized by other therapies.
The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health has stopped a clinical trial testing a drug treatment for pulmonary hypertension in adults with sickle cell disease nearly one year early due to safety concerns. In an interim review of safety data from 33 participants who completed 16 weeks of treatment, researchers found that, compared to participants on placebo (dummy pill), participants taking sildenafil (Revatio) were significantly more likely to have serious medical problems. The most common problem was episodes of severe pain called sickle cell crises, which resulted in hospitalization. No deaths have been associated with the drug in the clinical trial.
Pediatric researchers have found that a gene previously shown to be involved in the development of type 2 diabetes also predisposes children to having a lower birth weight. The finding sheds light on a possible genetic influence on how prenatal events may set the stage for developing diabetes in later childhood or adulthood.
Today, there are more ways than ever before to "get a little work done." From skin fillers to fat-reduction procedures, the options are endless for those looking to improve their appearance and boost their self-esteem. But with so many physicians and options from which to choose, consumers can be confused about where to start and who to trust to perform a cosmetic procedure.
Lawmakers push bill to fight Medicare fraud as part of health reform legislation.
Health officials are growing increasingly concerned over the impact the H1N1 (swine) flu is having on populations living in Latin America, a region "which accounts for around two-thirds of the 816 confirmed deaths so far from the disease," the AFP/channelnewsasia.com reports. "The outlook is especially unsettling for the estimated 380 million people grappling with winter in South America, where the A(H1N1) virus is speedily propagating," the news service writes. The article examines the number of H1N1 cases and deaths across countries and how government officials are working to prevent the spread of the virus (7/29).
Scientists in the US have found a way of slowing the growth of ovarian cancer tumors in mice by using nanoparticles to deliver suicide genes to
Diabetes affects nearly 24 million people in the United States. The most widespread form is type 2 diabetes, accounting for about 90 to 95 percent of all diagnosed cases of diabetes, according to the American Diabetes Association (ADA).
Older people with a history of cancer are more likely to have disabilities and be frail and vulnerable than older adults who have not had cancer, according to a study in the Journal of the National Cancer Institute, published online July 29.
Malaria parasites in western Cambodia have become resistant to artemisinin-based therapies, the first-line treatment for malaria, according to a study published in the New England Journal of Medicine. Resistance to the drugs makes them less effective and could eventually render them obsolete, putting millions of lives at risk.
People without health insurance will have another avenue for medical care beginning Aug. 1 when student volunteers at the Indiana University School of Medicine open the IU Student Outreach Clinic in a near eastside Indianapolis neighborhood.
The American Academy of Cosmetic Surgery announces the results of its 2009 Less Common Cosmetic Procedures consumer survey. While the media has coined these cosmetic procedures as "fringe" and made it seem that they are in high demand, it is important to clarify the facts. The results reveal that less common cosmetic procedures are generally over-hyped and over-analyzed.
The latest findings of the North Carolina-Louisiana Prostate Cancer Project reveal potential new targets for reducing racial disparities in prostate cancer survival and highlight the importance of the health care delivery system. The study reports differences in physician trust, access to care, and continuity of care between African American and Caucasian men which result in advanced prostate cancer at the time of diagnosis and contribute to the higher death rate among African American men. The study is published in the early view issue of Cancer online July 27, 2009.
Spiration, Inc., a developer of novel medical devices designed to benefit patients with acute and chronic conditions of the lung, announced today that several new clinical sites are now actively recruiting patients for participation in a pivotal trial of the company"s minimally invasive treatment for severe emphysema.
With a novel therapeutic delivery system, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center has successfully targeted a protein that is over-expressed in ovarian cancer cells. Using the EphA2 protein as a molecular homing mechanism, chemotherapy was delivered in a highly selective manner in preclinical models of ovarian cancer, the researchers report in the July 29 issue of the Journal of the National Cancer Institute.
Informa Healthcare - one of the world"s leading medical and scientific publishers- has announced that the new interactive http://www.informahealthcare.com site is now live and delivers online content from more than 180 peer-reviewed journals.
In cancer research, as in most other biomedical sciences, they are playing a key role: living cells, kept in sterile plastic containers with red culture media populating incubators in laboratories around the world. But do researchers always know what is really living in their culture dishes? Under the microscope, different cell lines are almost impossible to distinguish from each other. When these important research objects stop growing without apparent reason - is it because of the manipulations by the scientists or because of an invisible viral or bacterial infection?
Molecular Insight Pharmaceuticals, Inc. (NASDAQ: MIPI) announced that the European Medicines Agency (EMEA) has approved its Phase 3 protocol for Onalta (Yttrium-90 edotreotide). Onalta is the Company"s lead radiotherapeutic product candidate under development for the treatment of metastatic carcinoid and pancreatic neuroendocrine tumors in patients whose symptoms are not controlled by conventional therapy. The compound has shown the potential to selectively deliver lethal radiation to cancer cells. The proposed Phase 3 trial will confirm that administration of Onalta results in stabilization, regression or complete remission of the carcinoid tumor, and improves carcinoid-related symptoms when compared to a high-dose regimen of the current standard therapy for this disease, Sandostatin®. With EMEA"s approval of its proposed Phase 3 protocol in hand, Molecular Insight can proceed with the final clinical trial that will position Onalta for marketing authorization in the EU.
The Committee for a Responsible Federal Budget urges policymakers to make controlling health care cost growth the focus of health care reform (see Principle #1: Slowing Health Care Cost Growth ).
Anadys Pharmaceuticals, Inc. (Nasdaq: ANDS) announced finalization of the protocol for the Company"s Phase II trial of ANA598 in combination with pegylated interferon-alpha and ribavirin in hepatitis C patients. Allowance of the protocol has been received from the United States Food and Drug Administration (FDA), and patient dosing is expected to commence within the next several weeks.
Tiny particles carrying a killer gene can effectively suppress ovarian tumor growth in mice, according to a team of researchers from MIT and the Lankenau Institute.
The body"s nanomachines that read our genes don"t run as smoothly as previously thought, according to a new study by University of California, Berkeley, scientists.
A new rapid urine test for chlamydia in men identified 84% of infections, according to a study of 1,200 men published Tuesday in the British Medical Journal, Reuters reports. Chlamydia is the most common sexually transmitted infection among women and can be treated easily with antibiotics. However, the STI often goes undiagnosed and causes no symptoms in 70% of cases. It can lead to pelvic inflammatory disease, ectopic pregnancy and infertility. It also can make women more vulnerable to HIV.Rapid tests for chlamydia in men often have been inconclusive and uncomfortable, involving a painful swab of the urethra. The developer of the new test, Helen Lee of the University of Cambridge, said, "This has led to many cases of infection in men going undiagnosed and being transmitted to their female partners, with potentially more serious complications." The new test is "both accurate and swift, allowing men attending the clinics to be tested and treated on site in one visit," according to Lee. She said that the test already is approved in France and soon will be available in Italy, Spain, Portugal and other European countries (Reuters, 7/28).
The White House says opponents of the President"s health care reform effort are misrepresenting parts of the House and Senate legislation including a provision on end-of-life care. Critics say they fear health care reform could lead to excessive government intervention in end-of-life issues.
"The healthcare overhaul fight in Washington is bursting into America"s living rooms, and interests from many bands on the political spectrum are trying to transform an often wonky debate over 1,000-page bills into an emotional pitch that can be captured in 30 seconds," The Boston Globe reports.
Rush University will award 536 baccalaureate and graduate degrees at its 37th commencement ceremony on Saturday, June 13, at 1:45 p.m. at the UIC Pavilion, 525 South Racine, Chicago.
Prescribers treating patients who have had total hip or knee replacement surgery can access an independent review of the oral anticoagulant rivaroxaban (Xarelto) in the August issue of NPS RADAR.
The U.S. Food and Drug Administration has approved Colcrys to treat acute flairs in patients with gout, a recurrent and painful form of arthritis, and patients with familial Mediterranean fever (FMF), an inherited inflammatory disorder. The medication"s active ingredient is colchicine, a complex compound derived from the dried seeds of a plant known as the autumn crocus or meadow saffron (Colchicum autumnale).
University of Minnesota Project Eating Among Teens (EAT) researchers have identified factors that may increase overweight adolescents" risk of engaging in extreme weight control behaviors such as self-induced vomiting, the use of diet pills, laxatives, and diuretics, as well as binge eating. Overweight youth with certain socio-environmental, psychological, and behavioral tendencies, such as reading magazine articles about dieting, reporting a lack of family connectedness, placing a high importance on weight, and reporting having participated in unhealthy weight control behaviors, are more likely to suffer from eating disorders.
Nine-year-olds can and should learn CPR. A study of 147 schoolchildren, published in BioMed Central"s open access journal Critical Care, has shown that, although the smallest may lack the requisite strength, the knowledge of how to perform basic life support is well retained by young children.
The Health and Safety Executive (HSE) is urging companies to ensure that sufficient safety procedures and risk assessments are in place to properly protect staff.
A study by Kansas State University researchers is looking at how children perceive and interact with peers who have various undesirable characteristics, such as being overweight or aggressive.
The American Medical Student Association (AMSA), the nation"s oldest and largest, independent association for physicians-in-training, is pleased to present the graduates of the AMSA Foundation-VITAS End of Life Education Fellowship Program. Five medical students have spent the past six weeks immersing themselves in end of life (EOL) care issues.
Department of Health Secretary Everette James stressed the importance of immunizations in observance of National Immunization Awareness Month.
Recent questions about the death of Michael Jackson have focused media attention on the commonly used intravenous anesthetic propofol. In the April 2009 issue of Anesthesia & Analgesia, the leading clinical journal for anesthesiologists, Robert R. Kirby, James M. Colaw and Michael M. Douglas reported on a 24-year-old woman whose 2005 death was attributed to propofol toxicity.
King Pharmaceuticals, Inc. (NYSE: KG) announced additional information regarding the resubmission plan for the REMOXY® New Drug Application (NDA). The Company is not required by the Food and Drug Administration (FDA) to conduct clinical trials in order to provide additional safety or efficacy data in patients with moderate to severe chronic pain. However, as part of the resubmission plan, and in order to strengthen the NDA, King plans to conduct a likeability study and a pharmacokinetic trial in volunteers. The Company continues to anticipate the resubmission could occur mid-year 2010.
Allergan, Inc. (NYSE: AGN) announced that the United States Food and Drug Administration (FDA) has approved ACUVAIL(TM) (ketorolac tromethamine ophthalmic solution) 0.45%, an advanced, preservative-free formulation of ketorolac, a nonsteroidal anti-inflammatory drug (NSAID) indicated for the treatment of pain and inflammation following cataract surgery. Cataracts are a leading cause of blindness among older adults and cataract surgery is the most frequently performed surgical procedure in the United States, with more than 3 million procedures performed each year.1
GlaxoSmithKline (GSK) and Genmab A/S (OMX: GEN) announced preliminary top-line results from a Phase III study of ofatumumab administered intravenously for the treatment of rheumatoid arthritis (RA) in patients who had an inadequate response to methotrexate. The study met the primary endpoint, ACR20 at 24 weeks, which indicates a 20 percent or greater improvement in the number of swollen and tender joints, as well as improvements in other disease-activity measures.
GSK announced that it has notified the European Medicines Agency of its decision to withdraw the Marketing Authorisation Application (MAA) in the EU for mepolizumab for the treatment of hypereosinophilic syndrome (HES).
Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announces that it has received a Complete Response letter for INTUNIV TM (guanfacine) Extended Release from the Food and Drug Administration (FDA). This decision comes following labeling discussions with the FDA that did not result in agreement in time to meet the PDUFA date.
Parkinson"s disease is well-known for impairing movement and causing tremors, but many patients also develop other serious problems, including sleep disturbances and significant losses in cognitive function known as dementia.
Rush University Medical Center has opened the first multidisciplinary center in the Midwest for the treatment of asthma, addressing a chronic respiratory disease that affects 22 million Americans, including 6 million children.
As the House Energy and Commerce Committee marked up the health reform bill last night, "a series of amendments on both sides of the abortion debate [added] a political charge -- and a distraction -- to the progress of the legislation," Politico reports (Smith, 7/30).
Nearly one in four women living with HIV did not receive an annual Pap test in the year prior to being interviewed, according to a study published in the Aug. 1, Journal of Acquired Immune Deficiency Syndromes, Reuters reports. Women with HIV have an increased risk for cervical cancer, which the test detects, the article states. According to Reuters, "To see if guidelines for annual cervical cancer screening for HIV-infected women were being performed, ò€¦ [researchers] analyzed information on 2417 HIV-infected women from 18 states. Records showed that 23 percent of those interviewed had not undergone a Pap test during the year before the interview." The article states, "The risk of cervical cancer has not decreased since the introduction of highly active antiretroviral therapy for HIV infection, "highlighting the continued importance of cervical cancer screening in this population," health officials from" CDC note in the journal (Reuters, 7/30).
Researchers at the Center for Infection and Immunity (CII) at Columbia University Mailman School of Public Health are working with Argentina"s National Institute of Infectious Diseases, the National Administration of Laboratories and Health Institutes (ANLIS), and Roche 454 Life Sciences to decode the complete genomic sequences of influenza pandemic (H1N1) 2009 virus from patients with severe respiratory disease. The scientists will be comparing sequences of viruses associated with the current outbreak in Argentina with those found in other locations to determine if there are differences that may be linked to higher mortality rates or provide insights into virus evolution.
In a world first, Melbourne scientists have made a critical breakthrough in understanding the differences in the brains of people with schizophrenia.
UroToday.com - A recent European study demonstrated that 10-year mortality from cardiovascular disease and cancer was decreased in a population of 70 to 90 year olds who adhered to a Mediterranean diet, were physically active, had moderate alcohol consumption and did not smoke. There are also reports suggesting an inverse association between physical activity and risk of prostate cancer (CaP). Yet mechanisms linking lifestyle and longevity are not well investigated. This report in The Prostate investigates an animal model for the association between physical activity and development of CaP.
The ghrelin hormone not only stimulates the brain giving rise to an increase in appetite, but also favours the accumulation of lipids in visceral fatty tissue, located in the abdominal zone and considered to be the most harmful. This is the conclusion of research undertaken at Metabolic Research Laboratory of the University Hospital of Navarra, published recently in the International Journal of Obesity.
UroToday.com - We undertook a systematic review of the literature in reference to the use of ipsilateral adrenalectomy at the time of radical nephrectomy for the treatment of renal cell carcinoma. Important in the understanding of this is accurately defining..
By searching millions of DNA variations in the genomes of thousands of women with and without ovarian cancer, scientists have discovered a
Data presented today at the 8th European Congress on Menopause
The Medical Defence Union (MDU) has recruited three new medico-legal advisers in Scotland, bringing its team of experts north of the border to nine - its biggest ever team in the country.
As people age, the potential exists for those years to be the most rewarding and fulfilling time of their lives. However, major illness, retirement, the death of a spouse, and a shrinking circle of friends all may, in some cases, contribute to increased levels of stress and depression in the elderly. For that reason the chief of geropsychiatry for the Los Angeles Jewish Home - the largest single- provider of senior residential housing in the western United States - is offering seniors and their loved ones 10 warning signs that may trigger the need for assistance with mental health issues.
A paper just published in the British Journal of Pharmacology reports that a compound originally isolated from a soft coral (Capnella imbricate) could lead scientists to develop a new variety of treatments for neuropathic pain. This composite is collected at Green Island off Taiwan and could be a new option for treatment. Neuropathic pain is chronic and occasionally follows damage to the nervous system. Presently this type of pain is very poorly controlled by the usual analgesics: aspirin like drugs (NSAIDS) or even opioids like morphine. New treatments are urgently required.
"[T]he White House team is retooling its message and strategy, hoping a more modest approach will reinvigorate Obama"s signature domestic policy initiative and give him a first-year victory for Democrats to carry into the 2010 midterm elections," the Washington Post reports. An early focus on "fast, broad and bipartisan" reforms has given way to realities including a stiff Republican opposition, lack on consensus in his own party, and falling poll numbers. As a result, the administration and Democratic allies have missed a self-imposed August deadline, turned to harsher critiques of industry players and now appear open to both less-ambitious proposals, and procedural measures that could bypass GOP opposition to achieve a partisan reform bill (Connolly, 8/2).
Democrats are finding points they agree on in a tenuous accord for the message they want to relay to constituents during the August recess: The health insurance industry is the bad guy, The Washington Post reports.
Drug companies "boosted their lobbying in Washington during the three months (that) ended June 30 amid a flurry of congressional action on health care," while overall, "Washington"s lobbying business continued to slump as the economy pinched budgets at some big companies and trade associations," The Wall Street Journal reports. "Drug manufacturers increased lobbying spending 13% to $68 million in the second quarter from a year earlier, according to the data ò€¦ Overall, the health-care sector reported a 5% increase in lobbying expenditures to $133 million, making it the single largest spender on lobbying of the 10 major industry sectors tracked by the Center for Responsive Politics. Health-insurance companies increased lobbying activity by 11% to $7.8 million, according to the data" (Mullins and Farnam, 8/3).
The House Energy and Commerce Committee passed an amendment to their broad health reform bill giving drug makers 12 years of exclusive rights to market new biologic drugs, "a setback" to the administration and consumer advocates who hoped to make generic drugs more widely available, the Wall Street Journal reports. The panel voted 47-11 on the measure, which "would also allow "evergreening," the practice by pharmaceutical companies of making minimal adjustments to their drugs, such as creating extended-release versions, as a way to lengthen their monopoly."
Global Fund Audit Reveals Expired, Missing Drugs In Tanzania
About one in four HIV-positive women in the U.S. does not opt to undergo an annual Pap test for cervical cancer even though they are at an increased risk for the disease, according to a study in the Journal of Acquired Immune Deficiency Syndromes, Reuters reports. For the study, Alexandra Oster and colleagues from the Centers for Disease Control and Prevention analyzed the responses of 2,417 HIV-positive women from 18 states who participated in interviews for the Supplement to HIV/AIDS Surveillance Project.The researchers found that 23% of the women had not undergone a Pap test in the year before the interviews and that older age and a poorly functioning immune system were independent predictors of whether women had Pap tests.They wrote, "The risk of cervical cancer has not decreased since the introduction of (highly active antiretroviral) therapy, highlighting the continued importance of cervical cancer screening in this population." They added that "cervical cancer screening should be a high priority" for HIV-positive women (Reuters, 7/30).
Risk of human papillomavirus (HPV)-associated cancers is greater for people living with AIDS and increases with increasing immunosuppression, according to a new study published online July 31 in the Journal of the National Cancer Institute.
Whether it"s highlighted in major news headlines about Argentinean affairs and Ponzi schemes, or in personal battles with obesity and drug addiction, individuals regularly succumb to greed, lust and self-destructive behaviors. New research from the Kellogg School of Management examines why this is the case, and demonstrates that individuals believe they have more restraint than they actually possess - ultimately leading to poor decision-making.
Flasks, beakers and hot plates may soon be a thing of the past in chemistry labs. Instead of handling a few experiments on a bench top, scientists may simply pop a microchip into a computer and instantly run thousands of chemical reactions, with results - literally shrinking the lab down to the size of a thumbnail.
Heavy drinkers of beer and spirits face a much higher risk of developing cancer than the population at large, says a group of Montreal epidemiologists and cancer researchers. Their findings show that people in the highest consumption category increased their risk of developing oesophageal cancer sevenfold, colon cancer by 80% and even lung cancer by 50%.
Anorexic patients drastically reduce food intake and are often not capable of changing their behavior. This can lead to life-threatening weight loss. Using MRI technology, scientists at Heidelberg University Hospital have discovered for the first time processes in brain metabolism that explain this disturbed eating behavior.
Nurses who make home visits to children with asthma can help prevent half of those children from having to receive more serious treatment for their condition, suggests research published ahead of print in the Archives of Disease in Childhood.
Moffitt Cancer Center and Frantz BioMarkers, LLC have signed a license agreement on phospholipid biomarkers of ovarian cancer. Frantz BioMarkers, which has been granted exclusive worldwide rights to Moffitt"s interests in the biomarkers, will pay initiation, developmental milestone and license maintenance fees, and royalties on sales. Moffitt and Frantz BioMarkers will collaborate on ovarian cancer biomarker research, combining use of these licensed markers with lipid markers developed independently by Frantz BioMarkers.
The 128,000-member American College of Physicians (ACP) has endorsed the Preserving Patient Access to Primary Care Act of 2009 (H.R. 2350), introduced by Rep. Allyson Schwartz (D-PA). "Primary care is the best medicine for better health and lower costs," ACP noted, "and this is the best medicine for curing the growing crisis in primary care."
University of Michigan researchers have developed an animal model that provides strong evidence why imatinib, marketed as Gleevec, helps patients with chronic myeloid leukemia survive longer, but does not keep the disease from returning if treatment ends.
The study of the neural basis of language has largely focused on regions in the cortex - the outer brain layers thought by many researchers to have expanded during human evolution. Research at Brown University"s Department of Cognitive and Linguistic Sciences, reported in the September Issue of Cortex, published by Elsevier, adds to evidence that deeper, subcortical regions are also critical by pinpointing when Parkinson"s disease patients have difficulty while processing grammatically complex sentences. In Parkinson"s disease, degeneration of subcortical dopamine-secreting neurons leads not only to motor symptoms but often also to cognitive deficits.
Congressional Quarterly examines a "three-page concept paper" issued by the House Foreign Affairs Committee that lays out a plan to overhaul U.S. foreign aid. The committee suggests "giving the administration greater flexibility to control aid in exchange for greater public oversight and a performance- and need-driven allocation system," the news service writes. "The plan would reorganize aid programs around seven purposes, including "reducing poverty and alleviating human suffering," "supporting human rights and democracy," and "expanding prosperity through trade and investment,"" according to CQ. The House committee wants to enhance USAID"s role, "giving the agency a seat on the National Security Council and putting it in charge of the U.S. global AIDS plan and the Millennium Challenge Corporation," the news service writes.
The Guardian examines British Prime Minister Gordon Brown"s offer "to help some of the world"s poorest countries to make healthcare free - starting with pregnant women and children - in a push to widen access to doctors across Africa and Asia." According to the newspaper, the "Department for International Development (DfID) is among the largest donors to many developing countries, and has pledged to spend 6 billion pounds [about $10.2 billion] on health by 2015. Brown hopes to use an expanding aid budget to influence the way public services are delivered on the ground."
Third Person In China Dies Of Pneumonic Plague, Officials Seal-Off Area
The National Institutes of Health is launching the first integrated, drug development pipeline to produce new treatments for rare and neglected diseases. The $24 million program jumpstarts a trans-NIH initiative called the Therapeutics for Rare and Neglected Diseases Program, or TRND.
Nearly 75 percent of Americans suffer from some form of periodontal disease, the major cause of adult tooth loss. In addition, cardiovascular disease, the leading killer of men and women in the United States, is a major public health issue contributing to 2,400 deaths each day. And while these two conditions are seemingly unrelated, research suggests that managing one disease may reduce the risk for the other.
Elderly individuals who have a report of self-neglect or abuse submitted to a social service agency have an associated increased risk of death, according to a study in the August 5 issue of JAMA, a theme issue on violence and human rights.
New research suggests that universal intimate partner violence (IPV) screening in health care settings does not result in significant changes in subsequent reports of IPV or quality of life, according to a study in the August 5 issue of JAMA, a theme issue on violence and human rights.
The so-called "Khmer Rouge trials" now underway are likely to have an impact on the mental health of many Cambodians, according to a new study published in the August 5 issue of JAMA, a theme issue on violence and human rights.
Children have certainly mastered the art of selecting, negotiating and even refusing the chores their parents assign to them. This growth in personal autonomy at home over the last few decades could be the result of shrinking opportunities to participate in activities outside the home, without Mom and Dad looking over their shoulder, according to Dr. Markella Rutherford from Wellesley College in the US. Her analysis1 of back issues of the popular US magazine, Parents, maps how the portrayal of parental authority and children"s autonomy has changed over the last century. Her findings are published online in Springer"s journal Qualitative Sociology.
Professor Declan Murphy and colleagues Dr Michael Craig and Dr Marco Catani from the Institute of Psychiatry at King"s College London have found differences in the brain which may provide a biological explanation for psychopathy. The results of their study are outlined in the paper "Altered connections on the road to psychopathy", published in Molecular Psychiatry.
AccuVein LLC, maker of the AV300, the world"s first hand-held, non-contact vein illumination device, announced today that its medical device now carries a CE Mark, enabling the Company to commence European sales of AccuVein"s AV300.
The results of the first ever silver antimicrobial product trial in a nursing home environment, published in the British Journal of Community Nursing, reveal that levels of potentially deadly bacteria can be dramatically reduced using products treated with silver antimicrobial agents, creating cleaner and safer nursing homes for elderly residents across the UK.
Novavax, Inc. (Nasdaq: NVAX) announced it has manufactured a virus-like particle (VLP) vaccine candidate against the H1N1 pandemic influenza virus under current good-manufacturing practices (cGMP) at its new vaccine manufacturing facility in Rockville, MD. This milestone was accomplished in only 11 weeks after receiving the gene sequence for the H1N1 strain from the U.S. Centers for Disease Control. The Company was able to reach this manufacturing goal by employing proprietary, novel production technology which is not dependent on growing influenza virus in eggs. Chicken eggs are used to produce almost all of the world"s influenza vaccine supply. In addition, Novavax has produced essential reagents for measuring vaccine potency. The Company also has plans to produce additional batches of the pandemic H1N1 VLP vaccine to support human clinical studies and stands ready to assist with additional public health needs in the US as well as foreign countries.
UroToday.com - Vitamin D needs, especially in the northern latitudes where direct sunlight is unavailable for much of the year, are currently under scrutiny by members of both the scientific and medical communities. Vitamin D primarily plays a role in regulating calcium absorption in the gastrointestinal tract. However, epidemiologic and laboratory studies support the notion that vitamin D might play a role in chemoprevention - particularly of cancers of the colon, breast, ovarian, and prostate (Garland et al., Am J Public Health 2006;96:252-61) - immune modulation and prevention of certain autoimmune disorders (Cantorna et al., Exp Biol Med 2004;229:1136-1142), promoting bone integrity and preserving muscle mass (Montero-Odasso et al., Mol Aspects Med 2005;26:203-19), cardiovascular disease prevention (Wang et al., Circulation 2008;117:503-11), and prevention of all-cause mortality (Melamed et al., Arch Intern Med 2008;168:1629-37).
The American Civil Liberties Union has launched an effort to offer no-cost legal advice about an Illinois law requiring providers to notify an unmarried minor"s parents prior to performing an abortion, the AP/KWQC reports. The law, which took effect on Tuesday, was enacted in 1995. However, enforcement of the law was delayed by a series of court challenges. It requires that either a parent, grandparent, stepparent living in the home or a legal guardian be notified prior to a minor obtaining an abortion, although judges are permitted to grant exceptions. Abortion-rights opponents claim the law will ensure that parents are consulted so their children "aren"t forced into abortions," according to the AP/KWQC.In response to the law, ACLU has created a toll-free phone line and a Web site to assist girls seeking information about the judicial bypass process. Lorie Chaiten of the Illinois ACLU said the group also has been training lawyers to assist minors (AP/KWQC, 8/4).
Americans appear split over the president"s push for health care reform, a new CNN poll has found. "Fifty percent of those questioned in CNN/Opinion Research Corporation survey released Wednesday morning say they support the president"s plans, with 45 percent opposed. The results indicate a generational divide. ""Obama"s plan is most popular among younger Americans and least popular among senior citizens," says CNN Polling Director Keating Holland. "A majority of Americans over the age of 50 oppose Obama"s plan; a majority of those under 50 support it.""
"As they work to overhaul the nation"s healthcare system, President Obama and his congressional allies have pledged to help small-business owners such as Rhonda Ealy and Kelli Glasser," The Los Angeles Times reports. "Both businesswomen desperately want help. But they have strongly divergent views about what Washington should do, reflecting a broader debate about how to relieve the burden on the nation"s roughly 6 million small businesses." Ealy owns a coffee roasting company in Bend, Ore. with 13 employees, she says she "loves a Democratic proposal to create a government-run insurance plan, which she hopes will allow her to get her employees better coverage for less." Glasser, who "makes museum and trade-show exhibits" and has 87 employees, "hates a separate provision in the legislation that would place a new requirement on many businesses to cover their employees."
The Health and Safety Executive (HSE) is warning employers to ensure they assess the safety of equipment and ensure that it is sufficiently guarded after an employee"s left hand was severely damaged by the rotating blades of a valve that forms part of the extraction system in a metal recycling process.
During a presentation about the Health Agenda for the Americas at the "Seventh
"India has asked UNICEF to stop distributing millions of dollars worth of nutrition aid to children, saying it had been done without permission and at the expense of local food to fight hunger," Reuters reports. Since August 2008, UNICEF has invested about $2.4 million importing "a high energy relief treatment known as "Ready to Use Therapeutic Food" (RUTF)" for children with severe acute malnutrition in the states of Bihar and Madhya Pradesh, according to the news service (Williams, 8/4).
Malaria Cases, Deaths In Cambodia Increase
The addition of the anaesthetic lidocaine to radiocolloid injection for sentinel- lymph-node (SLN) mapping in patients with early breast cancer reduces injection pain and improves patient comfort without compromising SLN identification, and should be introduced as standard practice, concludes an Article published Online First and in the September edition of The Lancet Oncology.
The fifth annual report card from the Washington, D.C.,-based Appleseed Center for Law and Justice examining the district"s response to HIV gives the city "high marks for rapid testing, interagency coordination, surveillance and fighting the disease in the D.C. Jail," but finds that the city falls short in other areas, the Washington Examiner reports (Neibauer, 8/5). "The government also received above-average grades for leadership, managing grants to groups that help people with the illness, and monitoring the effectiveness of those programs," the Washington Post reports. However, "While Mayor Fenty and his administration deserve recognition for the continued support of ò€¦ numerous [HIV/AIDS Administration] initiatives, his public appearances and statements about the epidemic have fallen short of his enthusiasm for action inside the government," the report said. The report added that the district could do more to address HIV and recommended that HAA assess whether the improvements they have made are reducing the spread of the virus, according to the Post (Fears, 8/5).
"You"ll feel better after a good night"s sleep." We"ve all heard those words, but have we ever stopped to wonder about the mental health of people who just aren"t able to sleep well? Rachel Manber has, and the Stanford University School of Medicine researcher is trying to identify the best way to treat patients suffering from both depression and insomnia.
BSD Medical Corporation (NASDAQ:BSDM) announced that the U.S. Food and Drug Administration (FDA) has granted Humanitarian Use Device (HUD) designation for the company"s BSD-2000 Hyperthermia System for use in conjunction with radiation therapy for the treatment of cervical carcinoma patients who are ineligible for chemotherapy. This is the first of the two steps required to obtain Humanitarian Device Exemption (HDE) marketing approval, which requires BSD Medical to demonstrate the device"s safety and probable benefit in treating a disease or condition that affects fewer than 4,000 individuals in the United States per year. Now that FDA has granted the Humanitarian Use Designation for the BSD-2000, which confirms that the intended use population is fewer than 4,000 patients per year, BSD can file an HDE submission with the FDA. FDA has 75 days from the date of receipt of the HDE submission to grant or deny an HDE application. This period includes a 30-day filing period during which FDA determines whether the HDE application is sufficiently complete to permit substantive review. During this review, FDA may refine the indications for use which received HUD designation to finalize the indications for use for which HDE approval will be granted. This decision will be based on the data that are available to support the device"s HDE application. The company believes that the data previously submitted to FDA and reviewed by the agency in the company"s pending PMA application can be used to support the HDE approval, and that this previous review may expedite marketing approval for the BSD-2000.