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The Australian Community Continues To Value Nurses: Nurses Voted The Most 'ethical And Honest' Profession For The 15th Year Running
The Australian Nursing Federation (ANF) says the annual Roy Morgan professions survey, which shows nurses are regarded as the most "ethical and honest" of all professions, confirms the Australian public continues to appreciate the benefits nurses bring to Australia"s health.
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Solomon Islands Could See Increase In HIV Cases, World Health Organization Says
A recent estimate from the World Health Organization says that the number of HIV cases in the Solomon Islands could reach at least 350 by 2010, the Solomon Star News reports. The Star News reports that 12 new HIV cases were confirmed in 2008, although the actual number of new cases could be higher because of unreported cases. Of the 12 cases reported in 2008, eight were among women and four were among men, according to a health report.In addition, sexually transmitted infections, particularly syphilis and chlamydia, are prevalent among pregnant women in the country and overall condom use is low, indicating that people could be at a high risk for HIV, according to the report. The most at-risk populations include mobile workers, commercial sex workers, students and men who have sex with men. Twelve facilities in the country currently offer HIV tests, and a relatively low number of tests are conducted, according to the Star News. The Ministry of Health has partnered with various groups and agencies to address HIV/AIDS in the country, the Star News reports (Carter, Solomon Star News, 5/26).
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Embera NeuroTherapeutics Announces Expansion Of Management Team After Successful Completion Of Pilot Study Of Cocaine Addiction Treatment
Embera NeuroTherapeutics, Inc., a specialty pharmaceutical company developing novel treatments for drug addiction and obesity, announced today that the company has recently expanded its management team to prepare for its next stage of development, following the successful completion of the company"s pilot study of cocaine addiction treatment.

Endocrinology

Comment On The Study \'Filaggrin Gene Defects And Risk Of Developing Allergic Sensitisation And Allergic Disorders: Systematic Review And Meta-analysis

Dr Elaine Vickers, Research Relations Manager at Asthma UK, says: "This is an important piece of research which helps to explain why the majority of children with severe eczema go on to develop asthma in later childhood, as a result of their genetic make-up.

Scientists And Clinicians Meet To Understand "Rain Man"

UQ"s Queensland Brain Institute (QBI) will host a workshop tomorrow Tuesday July 14 for clinicians and scientists seeking to better understand the syndromes associated with a brain development condition made famous in the movie Rain Man.

NovImmune Successfully Completes NI-0801 Phase I Clinical Study

NovImmune, an immunology-focused biotech company

Eye Drug Trial Marks Milestone For Southampton\'s Groundbreaking Research Centre, UK

Eye experts based at Southampton General Hospital are trialling a drug that could repair vision without the need for surgery.

Illinois Public Health Director Presents At H1N1 Flu Preparedness Summit To Further Prepare For Possibility Of More Severe H1N1 Outbreak In The Fall

Speaking at a national summit this week on H1N1 flu preparedness, Dr. Damon T. Arnold, state public health director, stressed the need to prepare for the possibility the fall flu season could be more severe than normal.

Informa Healthcare To Launch Beta Site

Informa Healthcare - one of the world"s leading medical and scientific publishers - has announced that the new interactive http://www.informahealthcare.com beta site will go live in July.

TIBCO Spotfire Supports Top Scientists At German Cancer Research Center, Deutsches Krebsforschungszentrum

Scientists at the German Cancer Research Center Deutsches Krebsforschungszentrum (DKFZ) in Heidelberg, Germany, are using the enterprise analytics platform from TIBCO Software Inc. (NASDAQ: TIBX) for scientific research. This research includes looking at the mechanisms behind the causes of cancer, development of custom-tailored drugs, and understanding the types of cancer caused by infections.

FDA Takes Enforcement Action Against Three New Jersey Dietary Supplement And Protein Powder Manufacturers

The U.S. Department of Justice, on behalf of the U.S. Food and Drug Administration, has filed a complaint for permanent injunction against Quality Formulation Laboratories, Inc., American Sports Nutrition Inc., Sports Nutrition International LLC and Mohamed S. Desoky, who oversees operations at all three companies.

Three New Studies Give Clear Guidance On How To Better Recruit Volunteers For Alzheimer\'s Clinical Studies

Partnering with local physicians, working with local clinics, conducting educational seminars and health fairs were found to be the most effective tools in recruiting people for clinical studies

What Are Menstrual Cramps? What Causes Menstrual Cramps? What Are Period Pains?

Menstrual cramps, also known as dysmenorrhea or period pains, are painful sensations felt in the lower abdomen that can occur both before and during a woman"s menstrual period. The pain ranges from dull and annoying to severe and extreme. Menstrual cramps tend to begin after an egg is released from the ovaries and travels down the fallopian tube (ovulation).

DeCODE Discovers Second Common Genetic Risk Factor For Atrial Fibrillation And Stroke

Scientists at deCODE genetics (Nasdaq: DCGN) and colleagues from Europe and the United States today report the discovery of a common single-letter variant in the sequence of the human genome (SNP) conferring increased risk of atrial fibrillation (AF) and stroke. The findings will be integrated directly into the deCODE AF(TM) reference laboratory test for gauging individual risk of AF and stroke and helping to identify stroke patients who may benefit from enhanced monitoring for AF.

H1N1 Pandemic Flu Virus More Virulent Than Previously Thought

Researchers from the US and Japan studying the new H1N1 pandemic flu virus suggest that it is more virulent than previously thought. They

Obama Highlights U.S. Commitment To Reducing Maternal Mortality, HIV/AIDS In Address To Africa

In a speech before the Ghanaian Parliament, President Obama on Saturday reiterated U.S. support for public health programs that will reduce maternal mortality and the spread of HIV/AIDS in Africa, the New York Times reports. The speech, which was televised across the continent, focused on international relations with Africa and empowering African nations to address problems (Baker, New York Times, 7/12).In a portion of the speech about strengthening public health, Obama said that there has been "enormous progress ... in parts of Africa" in recent years. He continued, "Far more people are living productively with HIV/AIDS, and getting the drugs they need. But too many still die from diseases that shouldn"t kill them." He added, "When children are being killed because of a mosquito bite, and mothers are dying in childbirth, then we know that more progress must be made." Obama said that "incentives often provided by donor nations" often compel doctors and nurses to "go overseas, or work for programs that focus on a single disease," which "creates gaps in primary care and basic prevention." He also said that Africans must "make responsible choices that prevent the spread of disease, while promoting public health in their communities and countries."Obama noted that the U.S. has committed $63 billion "to meet these challenges." He added that the U.S. will not "confront illnesses in isolation" but instead "invest in public health systems that promote wellness and focus on the health of mothers and children" (AP/USA Today, 7/11). Obama also visited a women"s clinic to highlight U.S-backed programs to fight infant and maternal mortality (New York Times, 7/12).

Precision Imaging Ultrasound Software For Toshiba\'s Aplio XG Provides Unprecedented Image Clarity And Resolution

To help leading healthcare institutions increase productivity while improving patient care in diagnostic imaging, Toshiba America Medical Systems, Inc., has introduced Precision Imaging technology available on the Aplio™ XG ultrasound system. Precision Imaging technology acquires ultrasound images of unprecedented clarity and resolution, enabling users to see more clinical detail than ever before.

Fly Study Suggests Fasting May Not Be Key To Longer Life

Many studies on flies, mice, and more recently monkeys, have suggested that the key to a longer life is to restrict calorie intake, but a new study

House Seeks To Pay For Reform With New Tax On Wealthy

House Democrats are expected to begin marking up a health reform bill this week that members of the Ways and Means committee said "would cost less than $1 trillion over 10 years, [and would be] paid for chiefly by a combination of spending reductions in the health care system and a surtax on wealthy taxpayers," CQ Politics reports. "The surtax would be levied beginning in 2011. ň€¦ [T]here would be three income brackets - $350,000, $500,000 and $1 million for couples filing jointly, and $280,000, $400,000 and $800,000 for individuals - with a different rate at each level: "One, two, three [percent] - something like that,"" the committee"s chairman, Charles Rangel, D-N.Y., said (Wayne, 7/13).

UNAIDS Welcomes Continued Commitment Of Francophone Parliamentarians To The AIDS Response

The Assembly of parliamentarians of Francophone countries have adopted a resolution reaffirming their commitment to the AIDS response. The resolution, which was adopted during their annual assembly which was held from 3 to 6 July 2009 in Paris, gave a strong message that Francophone parliamentarians are continuing to put AIDS high on the agenda and push the response forward in their countries and beyond.

Physician-Owned Hospitals Under Fire In Reform Bills, While One M.D. Moves Into Franchising

The mood in Washington to compromise with hospitals, pharmaceutical makers and physician groups is not extending to physician-owned specialty hospitals, Time reports. "Any health-reform package passed by Congress will likely deal a major blow to an upstart competitor of many hospitals. Buried in the 850-page House health-reform draft is a provision that could in effect ban further construction of doctor-owned, for-profit specialty hospitals and prohibit existing ones from expanding. ň€¦ Senators Charles Grassley and Max Baucus, who lead the body"s powerful Finance Committee, have been vocal critics of the doctor-owned specialty-hospital model and the industry expects similar language to be included in any upcoming Senate health-reform bill as well."

Federal Program Cracks Down On Medicare Fraud In Houston

A federal program targets Medicare fraud in the Houston area as news of three cases representing at least $35 million in false claims emerged within the past week. The Houston Chronicle reports on the three cases, noting: "These Houston-area scams alleged in two FBI complaints and one Montgomery County indictment were among six reported nationally in a single week - representing at least $285 million in false billings, records showed. "This is an astounding amount," said Houston"s FBI spokeswoman Pat Villafranca. The $285 million is more than four times the amount stolen during robberies of U.S. banks during all of 2008, she said. This month, Houston became the fourth metropolitan area - joining Miami, Los Angeles and Detroit - to create a ramped-up fraud strike force. It goes by the acronym "HEAT," Health Care Fraud Prevention and Enforcement Action Team."

Bill Would Allow Federal Funding For Needle Exchange Programs

House Democrats on Friday as part of a spending measure to fund the Departments of Labor and HHS for fiscal year 2010, "unveiled legislation to lift a ban on federal funding for needle-exchange programs, a shift to try to reduce [HIV infections] but one that will probably spark a fight," Reuters/Boston Globe reports (7/11). The ban has been included in the annual spending bill in previous years. House Appropriations Committee Chair David Obey (D-Wis.) said, "Scientific studies have documented that needle exchange programs, when implemented as part of a comprehensive prevention strategy, are an effective public health intervention for reducing [HIV] infections and do not promote drug use" (Reuters, Pelofsky, 7/10). "The move is in keeping with a pledge [President] Obama made during the primaries to remove the prohibition on such funding, although the ban was carried in his budget request this year," CQ Today reports (Wolfe, 7/10). However, "Republicans are girding for a fight over the ban and lawmakers could try to restore it as the legislation moves through the House during the next two weeks," according to Reuters (7/10). The bill also addresses sex education and "appears to continue Democrats" slow march away from funding abstinence-only sex education," CQ reports (7/10).

Study Looks At HIV, Risk Behaviors Among Male Clients Of Sex Workers In Tijuana, Mexico

"A large percentage" of U.S. and Mexican men who regularly engage in sexual activity with sex workers in Tijuana, Mexico, do not use condoms and have a history of substance and alcohol use, according to a study published in the online journal AIDS, the Los Angeles Times" blog "L.A. Now" reports. The study, by researchers from Mexico and the University of California-San Diego, surveyed 400 men - both Mexico and U.S. residents - and found that half of the men had unprotected sex with a female sex worker within the last four months. Researchers noted that although Tijuana authorities require that sex workers be registered and tested regularly for HIV, "only about half of [sex workers] have registered or been tested," according to the blog. Thomas Patterson of the UC-San Diego"s department of psychiatry and the Veterans Affairs health center, said the findings indicate a need for an educational campaign targeting men who frequent sex workers (Perry, 7/11).

Kansas Organizations Sign Nationwide Petition Regarding Access To Condoms In CVS Stores

The Kansas City Star on Sunday examined a national petition -- signed recently by several local organizations -- requesting that CVS Caremark unlock condoms in all of its CVS pharmacy stores. "The petition, sponsored by the labor coalition Change to Win, said CVS stores tended to lock up condoms, especially in low-income neighborhoods with high numbers of minorities," the Star reports. CVS has said the practice is "a defense against shoplifters in stores where large numbers of condoms were stolen," according to the Star. CVS spokesperson Mike DeAngelis said not all condoms are locked in display cases. "DeAngelis also said the group behind the condom petition ň€¦ was mounting a smear campaign against CVS because of a labor dispute," the article states (Erickson, 7/12).

Needle Exchange Programs Could Save Texas \'Millions Of Dollars,\' Opinion Piece Says

Needle exchange programs (NEPs) "are an inexpensive public health intervention, especially when compared with the social costs of treating individuals with HIV or hepatitis-related chronic liver disease," Maureen Trotter, a pathologist and president of the Taylor-Jones-Haskell County Medical Society, writes in the Abilene Reporter News. She adds that legislation introduced this year in the Texas Legislature "to allow public health departments and organizations to establish disease control programs that provide for the anonymous exchange of used hypodermic needles and syringes for sterile ones, offer education and substance abuse treatment and blood-borne disease testing" failed to come to a floor vote. Trotter further discusses NEPs, citing data on outcomes of NEPs, and writes, "The costs of preventing one case of HIV is estimated between $4,000 and $12,000 via NEPs. The medical cost of treating a person infected with HIV is about $200,000," adding, "These programs, if implemented, could save Texas millions of dollars" (7/12).

Eliminating Polio Requires Global, Coordinated Effort -- Health Affairs Article Highlights Potential Risks, Rewards Of Worldwide Eradication

Eliminating polio everywhere will require global cooperation on several fronts, including lowering the cost for poor countries to vaccinate with inactivated polio vaccine (IPV), says a leading global health researcher in the July/August Health Affairs thematic issue on global health.

Cell Communication Following DNA Damage Has Implications In Aging And Cancer

When cells experiencing DNA damage fail to repair themselves, they send a signal to their neighbors letting them know they"re in trouble. The discovery, which shows that a process dubbed the DDR (DNA Damage Response) also controls communication from cell to cell, has implications for both cancer and aging. The findings appear in the July 13 online edition of the Nature Cell Biology.

Dilated Cardiomyopathy: Discovery Of Novel Gene

Researchers in the Heart Institute at Cincinnati Children"s Hospital Medical Center have discovered a novel gene responsible for heart muscle disease and chronic heart failure in some children and adults with dilated cardiomyopathy (DCM).

Higher Education Level, Greater Disability Associated With Treatment Timing In Parkinson\'s Disease

Individuals who have higher levels of education and who are more impaired by Parkinson"s disease appear to require treatment for their symptoms earlier than do other patients, according to a report posted online today that will appear in the September print issue of Archives of Neurology, one of the JAMA/Archives journals.

Plans To Improve Access To Occupational Health Services In Wales Announced

Plans to improve access to occupational health services in Wales to help tackle absenteeism and ill-health in the workplace will be announced today [Tuesday, 14 July] by Health Minister Edwina Hart.

Lupus Foundation Of America Web Chat Explores "Your Skin And Lupus"

Approximately two-thirds of the 1.5 million Americans living with lupus will develop some type of skin disease. Lupus is an autoimmune disease in which the immune system is unbalanced causing it to become destructive to any organ and tissue in the body. Skin disease in lupus can cause rashes or sores (lesions), most of which will appear on sun-exposed areas, such as a person"s face, ears, neck, arms, and legs. In addition, 40-70 percent of people with systemic lupus will find that their disease is made worse by exposure to ultraviolet (UV) rays from sunlight or artificial light. For this and other reasons, people with lupus are advised to take steps to protect themselves from exposure to UV light.

Health Net Federal Services Statement On TRICARE Award Announcement

Health Net Federal Services, LLC, the government operations division of Health Net, Inc. (NYSE:HNT), released the following statement today in response to the Department of Defense"s release of the TRICARE contract awards:

Cardiovascular Systems Announces First Patient Enrolled In COMPLIANCE 360 Degree Clinical Trial

Cardiovascular Systems, Inc. (CSI) (Nasdaq: CSII), a medical device company developing and commercializing innovative interventional treatment systems for vascular disease, announced today that the first patient has been enrolled in the COMPLIANCE 360 degree clinical trial. This prospective, randomized study will generate additional data on patient outcomes achieved in treating lesions above the knee with CSI"s Diamondback 360°® Peripheral Arterial System, a minimally invasive catheter for treating peripheral arterial disease (PAD).

Safer Transportation Of A Child With Special Needs

A new study by researchers from the Automotive Safety Program at Riley Hospital for Children and Indiana University School of Medicine published online July 13, 2009 in the journal Pediatrics reports that the parents of children with special health care needs are doing a good job with the selection of the appropriate child car seat but still need help in using it correctly.

Revision Of Lung Cancer Staging System

For the first time in more than 10 years, the universally accepted lung cancer staging system has been revised to more accurately reflect the prognosis for patients with non-small cell lung cancer (NSCLC).

Linking Genes, Brain, And Behavior In Children

It comes as no surprise that some babies are more difficult to soothe than others but frustrated parents may be relieved to know that this is not necessarily an indication of their parenting skills. According to a new report in Psychological Science, a journal of the Association for Psychological Science, children"s temperament may be due in part to a combination of a certain gene and a specific pattern of brain activity.

Citrus-Derived Flavonoid Prevents Obesity According To Study

A flavonoid derived from citrus fruit has shown tremendous promise for preventing weight gain and other signs of metabolic syndrome which can lead to Type 2 Diabetes and increased risk of cardiovascular disease. The study, led by Murray Huff of the Robarts Research Institute at The University of Western Ontario looked at a flavonoid (plant-based bioactive molecule) called naringenin. The findings are published online in the journal Diabetes.

Technology Similar To An Inkjet Printer Could Aid Toxin Detection

If that office inkjet printer has become just another fixture, it"s time to take a fresh look at it. Similar technology may soon be used to develop paper-based biosensors that can detect certain harmful toxins that can cause food poisoning or be used as bioterrorism agents.

Study Shows Decreased Risk Of Death From Opportunistic Infections With Earlier Antiretroviral Treatment

HIV-positive people with opportunistic infections who receive earlier antiretroviral treatment lower their risk of death compared with people who delay treatment, according to a new study conducted by the Stanford University School of Medicine and published in PLoS One, the San Jose Mercury News reports. The findings could lead to changes in recommendations for antiretroviral treatment protocol, specifically for patients diagnosed with HIV at an advanced stage, the Mercury News reports. The study included 262 HIV-positive participants at 39 health care sites across the U.S., and 20 participants in South Africa. During the yearlong study, the researchers found that among the participants who were treated promptly after developing an opportunistic infection, 14% died or developed another infection. The researchers also found that 24% of participants who deferred treatment for an average of 45 days died or had a decrease in health outcomes. According to the Mercury News, the question of when to start HIV-positive people on antiretroviral treatment remains unclear because of issues such as the high cost of medicines, side effects, and drug interactions or resistance. Andrew Zolopa, head of Stanford University School of Medicine"s division of infectious diseases and lead investigator of the study, said that physicians often treat HIV-positive people for an "acute crisis, then follow up later with treatment for HIV." He continues, "But that answer is wrong. The study shows very clearly that there is no safety downside to doing this -- and the benefit is quite substantial, reducing death by 50%." "Even in San Francisco, one of the first epicenters of HIV in the United States, we still find that many people present late in the course of their illness with an opportunistic infection," Mitch Katz, director of San Francisco"s Department of Health who was not involved in the study, said. He added, "This study shows that it is lifesaving to treat those persons with antiretroviral drugs while they are still in the hospital." Katz said that the results could lead to changes in HIV/AIDS practices worldwide. The International AIDS Society, CDC and the British AIDS Society have developed guidelines recommending that early antiretroviral treatment be considered in patients with opportunistic infections, Zolopa said. In addition, NIH is considering an international study to examine earlier initiation of antiretroviral treatment involving more than 9,000 people from both developed and developing countries (Krieger, San Jose Mercury News, 5/15).

Link Between Pesticide Levels In Blood And Parkinson\'s Disease

People with Parkinson"s disease have significantly higher blood levels of a particular pesticide than healthy people or those with Alzheimer"s disease, researchers at UT Southwestern Medical Center have found.

New Or Not? Cracking Cyclic Natural Products For New Drugs

Researchers have invented computational tools to decode and rapidly determine whether natural compounds collected in oceans and forests are new - or if these pharmaceutically promising compounds have already been described and are therefore not patentable.

Results From Trials Of DHA In Alzheimer\'s Disease And Age-Related Cognitive Decline

Results from two large studies using DHA, an omega 3 fatty acid, were

Mum Is Key To Solving Obesity

One of the UK"s leading weight loss organisations has backed calls for changes to the way that obesity is being tackled nationally after a new study suggested that children learn unhealthy lifestyle behaviour from parents of the same gender.

FDA Requires Labeling Change For Some Drugs Used To Prevent Rejection Of Kidney Transplants

The U.S. Food and Drug Administration said that it will require manufacturers of some immunosuppressant drugs used in kidney (renal) transplantation to update their labeling to reflect an increased risk of infections.

Statistical Press Notice: A&E Statistics - Quarterly Update, UK

The following statistics were released today by the Department of Health:

Evidence For A New Genetic Link To Therapeutic Efficacy For Alzheimer\'s Disease

Accera, Inc., a biotechnology company delivering breakthrough therapies in central nervous system diseases, today announced further evidence for genetic interactions impacting the efficacy of the ketogenic compound AC-1202 (Axona(TM)) in Alzheimer"s disease. New data from the company"s previously completed double-blind, placebo-controlled trial in patients with mild-to-moderate Alzheimer"s disease demonstrates an interaction between two genetic markers that strongly influence the therapeutic response in patients. Dr. Samuel Henderson, Executive Director of Research, will present these results at the 2009 International Conference on Alzheimer"s Disease (ICAD) sponsored by the Alzheimer"s Association.

Keryx Biopharmaceuticals, Inc. Commences Phase 1 Study Of KRX-0401 (Perifosine) In Recurrent Pediatric Solid Tumors At Memorial Sloan-Kettering Cancer

Keryx Biopharmaceuticals, Inc. (Nasdaq: KERX) announced today the initiation of a Phase 1 clinical study to evaluate KRX-0401 (perifosine) as a single agent treatment for recurrent solid tumors in pediatric patients. This Phase 1 study is now open for enrollment at Memorial Sloan-Kettering Cancer Center in New York City. Oren Becher, MD, Instructor, Department of Pediatrics, in coordination with Eric Holland, MD, PhD, Director of the Brain Tumor group at Memorial Sloan-Kettering Cancer Center, will act as the study"s Principal Investigator. The study announced is being fully funded by an external grant provided by a private organization.

World\'s First Deep Brain Stimulation Device Approved For Treatment Of Psychiatric Condition In Europe

Medtronic announced that Reclaim(R) Deep Brain Stimulation (DBS) Therapy has received CE (Conformite Europeene) Mark approval for the treatment of chronic, severe treatment-resistant obsessive-compulsive disorder (OCD). This is the first time that a deep brain stimulation therapy has gained approval in Europe for the treatment of a psychiatric disorder.

DACH1 A Key Protein For Tumor Suppression In ER+ Breast Cancer

Researchers from the Kimmel Cancer Center at Jefferson have identified a protein relationship that may be an ideal treatment target for ER+ breast cancer. The study was reported in the July 15 issue of Cancer Research.

Lesbian Women Feel Less Pressure To Have A \'perfect\' Body

A study that investigated whether a woman"s sexuality is related to her satisfaction with her appearance and eating behaviour is being presented today, 15th July 2009 at the British Psychological Society Psychology of Women"s Section annual conference.

AVMA House Of Delegates Welcomes New President; Takes Action To Combat Recession And Uphold Animal Welfare Policy

At the 146th Annual Convention of the American Veterinary Medical Association (AVMA), association leaders welcomed a new president and took action on animal welfare and antimicrobial policies as well as cost cutting measures.

Researchers Said Using Condoms Reduced Risk Of Genital Herpes

Researchers who analyzed pooled data from several studies concluded that using condoms was linked to a modest reduction in the risk of

Dr. Corry Installed As President Of American Veterinary Medical Association

Dr. James Cook officially handed over the title of American Veterinary Medical Association (AVMA) president to Dr. Larry Corry today at the 2009 AVMA Convention President"s Installation Luncheon in Seattle. Dr. Corry, a small-animal practitioner from Buford, Ga., becomes the 129th president of the AVMA.

Upcoming Health IT Decisions Could Spell Success Or Failure

"An unprecedented effort to computerize the nation"s hospitals and physician offices could be the key to reducing crippling health care costs - or a giveaway to technology vendors whose sales will be subsidized by taxpayers," the Dallas Morning News reports. The $45 billion, stimulus-funded effort in question could help reduce costs by cutting into the country"s $37.6 billion in medical errors each year, for instance. But, if requirements for providers seeking stimulus funding are too strict, the program could turn into "a bonanza for software vendors."

Today\'s Selection Of Editorials And Opinions

The Small Business Surtax The Wall Street Journal

Needle Exchange Program In Humboldt County, Calif., Forced To End; Officials Hoping For Federal Help

Health officials in Humboldt County, Calif., "will be watching closely" the debate expected to ensue over legislation introduced last week containing "a provision that would scrap the federal funding ban on needle exchange programs that has been in place for years," the Eureka Times-Standard reports. According to the Times-Standard, "This month, Open Door Community Health Centers" clinics in Arcata and Eureka quietly stopped administering the needle exchange program they have operated for almost a decade." Open Door Community Health Centers Chief Operating Officer Cheyenne Spetzler, said, "The footprint of the program just kept getting bigger." In addition, grant funding was often limited to covering the costs of the needles and not the costs of administering the programs, Spetzler said. County Department of Health and Human Services Programs Director Barbara LaHaie said the county is currently seeking alternatives to continue the program. However, "Without a reliable funding stream, that may prove difficult," the article states (Greenson, 7/13).

Also In Global Health News: HIV Drug Patents; Ethiopia HIV/AIDS Efforts; Music Fights Malaria; Food Security

British Members Of Parliament Want HIV Drug Patent Changes

Increased Risk Of Emphysema Following Childhood Exposure To Tobacco Smoke

Chronic exposure to tobacco smoke in childhood may contribute to early emphysema later in life, according to new research. Environmental tobacco smoke (ETS) is known to be associated with a variety of serious health problems, but it had not previously been associated with the development of emphysema over the life course. The data was presented on Tuesday, May 19, at the 105th International Conference of the American Thoracic Society in San Diego.

Study Examines Mechanism For Gene Alterations In Brain Tumors

In a related article appearing in the July 15 issue of JAMA, researchers have identified the mechanism linked to the alteration of certain genes cited by Bredel et al in the previous study.

Hormone Therapy Use Associated With Increased Risk Of Ovarian Cancer

Compared with women who have never taken hormone therapy, those who currently take it or who have taken it in the past are at increased risk of ovarian cancer, regardless of the duration of use, the formulation, estrogen dose, regimen or route of administration, according to a study in the July 15 issue of JAMA.

Repair Of Heart Defect Discovered Incidentally During Surgery May Not Have Clear Benefit

Patients who have a heart defect known as patent foramen ovale incidentally discovered and repaired during surgery for a different condition may have an increased odds of postoperative stroke, along with no clear benefit on short-term outcomes or long-term survival, according to a study in the July 15 issue of JAMA.

IQ Explains Some Of The Difference In Heart Disease Between People Of High And Low Socio-economic Status

A unique study looking at the difference in cardiovascular disease (heart disease and stroke) and life expectancy between people of high and low socio-economic status has found that a person"s IQ may have a role to play.

Memory Test And PET Scans Detect Early Signs Of Alzheimer\'s

A large study of patients with mild cognitive impairment revealed that results from cognitive tests and brain scans can work as an early warning system for the subsequent development of Alzheimer"s disease.

Protalix Holds Pre-NDA Meeting With FDA For PrGCD For The Treatment Of Gaucher Disease

Protalix BioTherapeutics, Inc. (NYSE-Amex:PLX), announced that the Company held a pre-NDA meeting with the U.S. Food and Drug Administration (FDA). The purpose of the meeting was to discuss the a proposed new drug application (NDA) submission for prGCD, a new proprietary plant-cell expressed recombinant form of glucocerebrosidase, for the treatment of Gaucher disease and to confirm the clinical, nonclinical and chemistry requirements for the proposed NDA filing.

Need For Accurate Estimates Of The Severity Of The New H1N1 Virus

A paper published on bmj.com reports that there is a need for precise estimates of the severity of the new H1N1 virus. Experts need to assess in particular how many deaths might arise over the course of the pandemic. This will be the focus of healthcare planning over the upcoming months.

FDA Approves NovoLog(R) Labeling Update

Diabetes patients taking NovoLog((R)) (insulin aspart [rDNA origin] injection) can now use the insulin in their pump for up to six days following the U.S. Food and Drug Administration (FDA) approval of a labeling change, diabetes care company Novo Nordisk announced today.(1) The previous label allowed for NovoLog((R)) to be stored in the pump reservoir for two days. This makes NovoLog((R)) the first and only rapid-acting insulin with this extended in-use time.

Study To Assess Hip Exercises As Treatment For Osteoarthritis In The Knee Joints

Researchers at Rush University Medical Center are testing a novel regimen of hip-muscle exercises to decrease the load on the knee joints in patients with osteoarthritis. The goal is not only to relieve pain but also, possibly, to halt progression of the disease.

Sotomayor Calls Roe \'Settled Law,\' Says Health Of Woman Must Be Considered

During the second day of her Senate Judiciary Committee confirmation hearings, Supreme Court nominee Sonia Sotomayor said she views the 1973 Roe v. Wade decision legalizing abortion in the U.S. as settled law reaffirmed by subsequent Supreme Court rulings, the Washington Post reports (Goldstein et al., Washington Post, 7/15). At Tuesday"s hearing, lawmakers pressed Sotomayor on her views regarding abortion rights and Supreme Court precedent, the New York Times reports. She told committee members that the contraception rights case that is the foundation for Roe was "the precedent of the court, so it is settled law." She also said the 1992 ruling in Casey v. Planned Parenthood "reaffirmed the core holding of Roe," adding, "That is the precedent of the court and settled law in terms of the holding of the court" (Savage, New York Times, 7/15). Sotomayor said that "there is a right of privacy" and that the Supreme Court "has found it in various places in the Constitution." She cited the Fourth Amendment protection against unreasonable search and seizure and the 14th Amendment guaranteeing equal protection of the law (AP/Yahoo! News, 7/14).Sen. Orrin Hatch (R-Utah) asked Sotomayor if she considered the 2007 ruling in Gonzales v. Carhart an example of settled law. In the case, the court voted 5-4 to uphold the Partial-Birth Abortion Ban Act of 2003. The ruling was the first time since Roe that the court upheld an abortion restriction that made no exception for the health of the woman, the Times reports. In her response, Sotomayor said that "[a]ll precedent of the Supreme Court I consider settled law, subject to the deference the doctrine of stare decisis would counsel," although she did not address the health exception component of the Gonzales case.Sen. Dianne Feinstein (D-Calif.) later pressed Sotomayor to elaborate on her views on Gonzales. Feinstein noted that at least seven Supreme Court rulings prior to the 2007 case stated that abortion laws "cannot put a woman"s health at risk." She added that Gonzales "essentially removed this basic constitutional right for women." Feinstein asked Sotomayor, "When there are multiple precedents and a question arises, are all the previous decisions discarded, or should the court re-examine all the cases on point?" Sotomayor replied that she does not consider Gonzales to be a precedent making it settled law that health exceptions for abortion laws are constitutionally unnecessary. She said, "That was, I don"t believe, a rejection of its prior precedents," which are "still precedents of the court." Sotomayor added that the "health and welfare of a woman must be -- must be a compelling consideration." Feinstein pressed Sotomayor to clarify that she meant that it is still settled that abortion restrictions must have health exceptions. Sotomayor said, "It has been a part of the court"s jurisprudence and a part of its precedents. Those precedents must be given deference in any situation that arises before the court" (New York Times, 7/15).Sen. Lindsey Graham (R-S.C.) asked Sotomayor if the Constitution prohibits Congress or state legislatures "from defining life or regulating the rights of the unborn or protecting the right of the unborn in the first trimester?" Sotomayor began to cite the 14th Amendment to answer the question. Graham interrupted, asking, "[I]s there÷ anything in the document written about abortion?" Sotomayor said the "word "abortion" is not used in the Constitution, but the Constitution does have a broad provision concerning a liberty provision under the due process" clause (Holman, "NewsHour with Jim Lehrer," PBS, 7/14).Graham also asked Sotomayor about her work with the Puerto Rican Legal Defense and Education Fund, which had submitted legal briefs in the past that supported public funding for abortion coverage for low-income women. Sotomayor served on the group"s board from 1980 to 1992. She said that she "wasn"t aware of what was said in those briefs." She noted that she had served on the board but was not a lawyer for the gro

Ariz. Gov. Signs Bills Increasing Abortion Restrictions, Updating Existing Statutes

Arizona Gov. Jan Brewer (R) on Monday signed into law a bill (HB 2564) that mandates a 24-hour waiting period and in-person counseling with a doctor before women can receive abortion care, the AP/Yahoo! News reports. The law requires doctors to list risks and alternatives and describe the fetus"s probable characteristics. It also makes an existing parental consent law more restrictive for minors seeking abortion care and allows health care workers to refuse to dispense emergency contraception on moral or religious grounds.Planned Parenthood Arizona said the measure "creates barriers, increases costs and denies access to services and providers to women who seek abortion care." Bryan Howard, the affiliate"s president, said, "Women will be forced to delay their care, in turn increasing their health risks." In signing the measure, Brewer "set a new course" from former Gov. Janet Napolitano (D), who vetoed all bills that restricted abortion rights during her six years as governor, the AP/Yahoo! News reports.Brewer Signs Law Revising "Partial-Birth Abortion" Ban Brewer also signed legislation (HB 2400) that revises an Arizona law banning so-called "partial-birth" abortion except when the procedure is necessary to save the woman"s life. A federal judge in October 1997 ruled that a state law banning the procedure was unconstitutional, but the Supreme Court in 2007 upheld a similar federal law. The new law is intended to align the 1997 state law with the federal statute, according to the AP/Yahoo! News.The new law specifies a punishment of up to two years in prison. It allows a doctor charged under the law to seek a hearing before a state regulatory board to determine if the doctor"s actions were necessary to save the woman. Advocates of the bill say that it will allow local authorities to enforce the ban on the procedure (Davenport, AP/Yahoo! News, 7/13).

NICE Issues Positive Final Appraisal Determination Recommending The Use Of Basilea\'s Toctino

Basilea Pharmaceutica Ltd. (SWISS: BSLN) announces that the National Institute for Health and Clinical Excellence (NICE) issued the Final Appraisal Determination (FAD) recommending the use of Toctino® (alitretinoin) within its licensed indication, as a treatment option for adults with severe chronic hand eczema that has not responded to potent topical corticosteroids.

Despite Some Progress, Key Senators Say August Deadline A Longshot

One day after President Obama told lawmakers to speed up their pace, three key Finance Committee senators expressed doubts about meeting the President"s August deadline for passing a reform proposal, Politico reports. Sen. Kent Conrad, D-N.D., said he doesn"t "see how" his colleagues can confirm the new Supreme Court nominee, Sonia Sotomayor, and pass a health bill in the time left before the August recess.

Proteomics: Finding The Key Ingredients Of Disease

The winner of the chilli cook-off, usually has a key secret ingredient, which is hard to identify. Similarly, many diseases have crucial proteins, which change the dynamics of cells from benign to deadly. New findings from an international collaboration, involving McGill University, the Research Institute of the McGill University Health Centre (MUHC) and the Human Proteome Organisation (HUPO) just made identifying these changes one step easier. Their findings published in Nature Methods, show how to improve protein analysis to tease out relevant potential disease-causing molecules.

Internists Note \'Close Alignment\' With Policies In America\'s Affordable Health Choices Act Of 2009 -ACP Urges Approval By House Committees

The president of the American College of Physicians (ACP) today told the chairmen of the House Ways and Means, Energy and Commerce, and Education and Labor Committees that America"s Affordable Health Choices Act of 2009, H.R. 3200, is "closely aligned" with ACP policies on coverage, workforce, and payment and delivery system reform.

Bio Manufacturers Poised To Follow Senate Victory With House Win

"A veteran California lawmaker with ties to the biotechnology industry said she thinks her proposal to protect brand-name biologic makers has enough support to carry in the House Energy and Commerce Committee," Dow Jones Newswires/Wall Street Journal reports. The proposal, by Rep. Anna Eshoo, D-Calif., would protect brand-name biologic products from competition for 12 years. A similar proposal cleared the Senate health committee earlier this week.

Medicare Fraud Taints California Device Maker And New Jersey Clinic

A California device maker settles a Medicare fraud case while a New Jersey doctor and his office manager are accused in a Medicare fraud scheme.

New Hampshire\'s Medicaid Program Almost Out Of Money

"Rising unemployment and spiking Medicaid and welfare caseloads have put [New Hampshire"s] most recent budget to the test just two weeks after its adoption," New Hampshire Public Radio reports. The state"s Medicaid caseload is just 39 enrollees away from putting the "state"s Medicaid budget in the red."

Researchers Id Brain-Protecting Protein

Johns Hopkins researchers have discovered a novel protein that can protect brain cells by interrupting a naturally occurring "stress cascade" resulting in cell death.

Media Looks At Surgeon General Nominee\'s Potential Influence On HIV/AIDS, Other Health Issues

The AP/Lexington Herald-Leader on Tuesday examined the nomination of Alabama physician Regina Benjamin for U.S. Surgeon General by President Obama, the history of the position and how former Surgeon Generals have addressed health issues such as HIV/AIDS (Stobbe, 7/14). According to Advocate.com, "During her speech accepting the nomination, Benjamin acknowledged her familiarity with HIV complications and issues, as her brother died at the age of 44 of an HIV-related illness. Having such a personal experience, especially a loss, due to HIV/AIDS could have a strong impact on her policy and public health campaigns, [Phil Curtis, director of government affairs at AIDS Project Los Angeles], told Advocate.com on Tuesday." The article states, "Curtis said that Benjamin has the ability to reach out to communities that have been largely underserved by efforts to reduce the rate of infection," and she "will also be able to contribute to Congress"s current debate on health care policy, including strategies for early HIV prevention, and accessibility to prescription drugs" (Garcia, 7/14).

Vehicle Designed For Blind To Take The Wheel

A student team in the Virginia Tech College of Engineering is providing the blind with an opportunity many never thought possible: The opportunity to drive.

Targeted Cancer Treatment Following Breakthrough In Radiotherapy

Current radiation therapy treatment damages a patient"s healthy tissue as well as eradicating the tumour it is intended to destroy, making the treatment especially invasive and often causing nasty side effects.

Alzheimer\'s Disease: Vitamin D, Curcumin May Help Clear Amyloid Plaques

UCLA scientists and colleagues from UC Riverside and the Human BioMolecular Research Institute have found that a form of vitamin D, together with a chemical found in turmeric spice called curcumin, may help stimulate the immune system to clear the brain of amyloid beta, which forms the plaques considered the hallmark of Alzheimer"s disease.

Controling Concurrent Hepatitis B Infection By Focusing HIV Treatment

Prolonged use of highly active antiretroviral therapy (HAART) to treat people infected with both HIV and hepatitis B (HBV) helps to better control the hepatitis B infection and could delay or prevent liver complications, according to a new study by researchers at Wake Forest University School of Medicine.

Greater Academic Disengagement In US Teens

In the United States, adolescence is a time when many teens become less interested in academics. A new longitudinal study has found that this disengagement is greater for American teens than for Chinese teens.

Teens Sensitive To Others\' Perceptions Of Them

Young adolescents care a lot about what others think about them. A new study confirms this using brain-mapping techniques that shed new light on this complex period of social development.

AGA Medical Corporation Receives European CE Mark Approval For AMPLATZER(R) Vascular Plug 4

AGA Medical Corporation has received European CE Mark approval for its AMPLATZER® vascular plug, AVP 4. The device, which is indicated for arterial and venous embolizations in the peripheral vasculature, uses AMPLATZER"s proven mesh-braided Nitinol technology and may eliminate the need for catheter exchange, giving physicians a more efficient procedure. AGA Medical will begin marketing the AVP 4 in Europe immediately.

Aetna Encourages Parents To Consider Their Student\'s Health Insurance Options When Preparing For College

For parents, summer is the ideal time to ensure college students are prepared academically and financially for campus life. From selecting courses to buying textbooks, there are a number of decisions to be made; however, one important decision - health insurance - is often overlooked. As part of the college preparation process, Aetna (NYSE: AET) encourages parents to also consider their student"s health insurance options before heading off to school.

Sapient Delivers New Online Multilingual Re To Support Thousands Of Families Affected By Rare Congenital Syndrome

Sapient (NASDAQ: SAPE) announced that it has designed and delivered a Web-based multilingual solution to support the efforts of CdLS World, an international federation of non-profit organizations committed to assisting those affected by Cornelia de Lange Syndrome (CdLS), a rare congenital disorder. While there is as yet no cure for CdLS, information and access to early therapeutic interventions and therapies is the key to helping children with CdLS reach their full potential. Sapient"s Ask the Doctor - which can be accessed at http://www.cdlsworld.org or through local CdLS country websites - brings a vast online re of up-to-date, relevant medical information to families and medical professionals around the world.

New Research Shows: Neurofeedback Is An \'Evidence-Based\' Treatment For ADHD

Neurofeedback - also called EEG Biofeedback - is a method used to train brain activity in order to normalize Brain function and treat psychiatric disorders. This treatment method has gained interest over the last 10 years, however the question whether this treatment should be regarded as an Evidence-Based treatment was unanswered until now. Tomorrow a study will be published in the scientific journal "EEG and Clinical Neuroscience" demonstrating that Neurofeedback can indeed be regarded as an evidence-based treatment for Attention Deficit- / Hyperactivity Disorder (ADHD).

New Information About DNA Repair Mechanism Could Lead To Better Cancer Drugs

Researchers at Washington University School of Medicine in St. Louis have shed new light on a process that fixes breaks in the genetic material of the body"s cells. Their findings could lead to ways of enhancing chemotherapy drugs that destroy cancer cells by damaging their DNA.

Nurses Call On Rep. Miller To Support Amendment Allowing States To Enact Single-Payer Health Reform

With debate underway in the House Education and Labor Committee today on the sweeping healthcare reform bill in that body, the nation"s largest organization of registered nurses today called on Committee Chair George Miller to support a critical amendment that would enable individual states to go a step farther and adopt single-payer, Medicare-for-All style reforms.

New Obama Administration Policy To Allow U.S. Asylum For Abused Foreign Women

A recent Obama administration legal filing clears the way for foreign women who have experienced severe domestic beatings and sexual abuse to receive asylum in the U.S., the New York Times reports. The administration stated its position in an April immigration appeals court filing involving a Mexican woman, identified only by her initials, who is seeking asylum in the U.S. because of fear that her abusive common-law husband would kill her. The Times reports that the woman recently consented to having her confidential case documents disclosed to the newspaper.The filing reverses the government"s stance under former President George W. Bush. According to the Times, lawyers say that the Obama administration "has marked a clear, although narrow, pathway for battered women seeking asylum, ... after 13 years of tangled court arguments." Bush administration lawyers had argued as recently as last year that the Mexican woman and others like her could not meet the standards of U.S. asylum law, the Times reports. Applicants for U.S. asylums or refugee status must show a "well-founded fear of persecution" because of race, religion, nationality, political opinion or "membership in a particular social group." The legal debate has been whether women can be included under those terms. According to the Obama administration"s court filing, foreign women who experience abuse would have to prove that their abusers treat them as subordinates and little better than property. They would also have to show that abuse is widely accepted in their country. In addition, they would need to demonstrate that they are unable to find protections from their countries" institutions or by moving somewhere else in their country. The policy does not apply to women fleeing genital mutilation, the Times reports. The Department of Homeland Security has not recommended asylum for the woman. However, DHS senior lawyers wrote in the filing that "it is possible" for her "and other applicants who have experienced domestic violence could qualify for asylum."Under the Clinton administration, Attorney General Janet Reno proposed regulations to clarify the asylum law, but they have never taken effect. DHS lawyers in 2004 raised the possibility of asylum for domestic violence victims, but it was never put into practice in immigration court, according to Karen Musalo, director of the Center for Gender and Refugee Studies at the University of California Hastings College of the Law. "This really opens the door to the protection of women who have suffered these kinds of violations," Musalo said. DHS officials said they now are returning to the 2004 position of stipulating conditions narrow enough to allow domestic violence victims to gain asylum in only a limited number of cases. Matt Chandler, a DHS spokesperson, said, "Although each case is highly fact-dependent and requires scrutiny of the specific threat an applicant faces, the department continues to view domestic violence as a possible basis for asylum in the United States" (Preston, New York Times, 7/16).

FDA Approves Opioid Pain Reliever With Required Risk Reduction Plan

The U.S. Food and Drug Administration approved Onsolis, medication intended for certain patients with cancer to help manage breakthrough pain - severe flares of pain that break through regular pain medication.

Proposals May Limit Insurance Choices And Squeeze Some Middle Earners

"President Obama and leading Democrats have stressed that people who like their employer-sponsored insurance would be able to keep it, under a health care overhaul. But they haven"t emphasized the flip side: That people who don"t like their coverage might have to keep it," Kaiser Health News reports. "Under the main health bills being debated in Congress, many people with job-based insurance could find it difficult to impossible to switch to health plans on a new insurance exchange, even if the plans there were cheaper or offered better coverage. The restrictions extend to any government-run plan, which would be offered on the exchange." But "there are a few exceptions: Workers would be allowed to buy insurance through the exchange if their job-based coverage gobbled up too much of their incomes or was too skimpy. Also, under the House proposal, people could get insurance through the exchange if they paid their entire premiums - a cost that would be prohibitive for many workers."

Insurer, Tech Vendor Plan Major \'Telehealth\' Network

A major health insurer, UnitedHealth, and a computer networking company, Cisco Systems, are teaming up to create "a network of virtual clinics to make medical care available in offices, stores and rural areas around the country," Bloomberg reports. Under the plan, United Health will spend "tens of millions" to set up the clinics using equipment provided by Cisco. "Cisco and UnitedHealth see a growing market in remote doctoring as lawmakers consider an overhaul of U.S. health care, said Jim Woodburn, a UnitedHealth vice president. The stimulus package approved in February included $6 billion for "telehealth" initiatives" (Nussbaum, 7/15).

South American Health Ministers Gather In Argentina To Discuss H1N1 Preparedness

The health ministers of six South American countries gathered in Buenos Aires, Argentina, on Wednesday to "coordinate defenses against" the H1N1 (swine flu) virus which has killed nearly 200 people in the region," the AFP/Google.com reports. Ministers from Argentina, Bolivia, Brazil, Chile, Paraguay and Uruguay used the meeting to voice concern over the rapid spread of the H1N1 virus in their countries, which are now in the southern hemisphere"s winter months, and discuss ways to share supplies to help prevent the spread of the virus. The article includes the individual strategies being taken by some South American countries (7/15).

Genome Sequencing Of Schistosomiasis Parasites Could Promote Drug Development

Researchers have sequenced the genomes of two parasites that cause bilharzia or schistosomiasis - a disease transmitted by water-borne snails that affects more than 200 million people worldwide - "revealing potential weaknesses that could be exploited by drug developers," Nature reports (Smith, 7/15).

ATryn Effectively Prevents Serious Blood Clots

Data presented at the annual meeting of the International Society on Thrombosis and Haemostasis (ISTH) in Boston show that ATryn® (Antithrombin [Recombinant]) safely prevents peri-operative and peri-partum acute deep vein thrombosis (DVT) or other venous thromboembolic events in patients with hereditary antithrombin deficiency (HD AT). ATryn is not indicated for treatment of thromboembolic events in HD AT patients. Additionally, data validate dosing algorithms that, along with AT activity monitoring, allow physicians to normalize antithrombin levels during the high-risk situations of surgery and childbirth.

Largest Ever Study Of Suicide In The Military

Four of the nation"s leading experts in suicide research, including Dr. John Mann of Columbia University Medical Center, will carry out the largest study of suicide and mental health among military personnel ever undertaken, with $50 million in funding from the U.S. Army. The announcement came today from the National Institute of Mental Health (NIMH), which signed a memorandum of agreement with the Army in October 2008 authorizing the NIMH to undertake the investigation with Army funding. Study investigators aim to move quickly to identify risk and protective factors for suicide among soldiers and provide a science base for effective and practical interventions to reduce suicide rates and address associated mental health problems.

Healthier, Longer-Lasting Fish Filets With Edible Coating

Consumers may be able to eat longer-lasting, potentially healthier fish fillets if research at Oregon State University makes its way to the supermarket.

Training Improves Multitasking Ability

Training increases brain processing speed and improves our ability to multitask, new research from Vanderbilt University published in the June 15 issue of Neuron indicates.

Breakthrough In The Treatment Of Bacterial Meningitis

It can take just hours after the symptoms appear for someone to die from bacterial meningitis. Now, after years of research, experts at The University of Nottingham have finally discovered how the deadly meningococcal bacteria is able to break through the body"s natural defence mechanism and attack the brain.

Nepean Dyspepsia Index Applies To Functional Dyspepsia In China

FD, a common non-organic disease in the world, greatly affects a patient"s quality of life. However, treatment of FD is still controversial and no single therapy is uniformly effective, due, in part, to absence of a reliable evaluation instrument. The Nepean Dyspepsia Index (NDI), measuring both symptom scores and impairment of the dyspepsia-specific health-related quality of life in FD patients, has been designed to diagnose FD and has been translated into several languages. Moreover, its utility has been proved to be validated by researches in western countries. However, DI has not been translated and validated in China.

Serum Bile Acid Profiling For Inflammatory Bowel Disease Characterization

Based on serum bank material, BA profiling was applied in IBD patients and healthy controls which showed that most but not all BA species were decreased to a different extent in CD and UC. BA decreases were highly pronounced in CD patients with surgical interventions in the gut. On the other hand, UC patients with additional liver and gallbladder diseases showed clearly increased levels of those BAs that are synthesized directly in the liver (primary BAs), or subsequently modified by intestinal bacteria (secondary BAs). Furthermore, a marked decrease in the toxic BA lithocholic acid (LCA) was found together with a marked increase in its physiological detoxification product, hyodeoxycholic acid (HDCA), irrespective of the IBD phenotype or clinical manifestation, which showed accelerated detoxification activity in IBD patients. Thus, serum BA profiling might serve as an additional diagnostic tool for IBD characterization and differentiation. In combination with expression profiles of nuclear pregnane X receptor (PXR)-regulated genes, it might allow us to estimate the BA detoxification potential of IBD patients.

Surprising Findings May Yield Insights Into Human Developmental Disorders: Researchers Discover Evolutionary Event Underlying The Origin Of Dachshunds

A single evolutionary event appears to explain the short, curved legs that characterize all of today"s dachshunds, corgis, basset hounds and at least 16 other breeds of dogs, a team led by the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, report. In addition to what it reveals about short-legged dogs, the unexpected discovery provides new clues about how physical differences may arise within species and suggests new approaches to understanding a form of human dwarfism.

Diabetes Wounds Healed With Oxygen Under Pressure

Every 30 seconds a person somewhere in the world loses a lower limb to amputation due to diabetic foot disease.

Disruptions In HIV Drug Supplies And Funding Endangering Patients\' Lives

Recent disruptions in the supply of anti-retroviral (ARV) drugs and other essential medical items in at least six African countries are putting HIV patients" lives at risk, said the international medical humanitarian organization Doctors Without Borders/Mç©decins Sans Frontiç¨res (MSF) today, in advance of the International AIDS Society Conference in Cape Town, South Africa.

Bionovo\'s Estrogen Receptor Beta Selective Drugs Have Unique Gene Expression And Cell Type Specificity

Bionovo, Inc. (Nasdaq: BNVI) announced that a study of the gene regulation in multiple cell lines by several of their estrogen receptor beta (ERb) candidates will be published in Public Library of Science One.

Expert Available To Discuss CDC Report Showing Poison Deaths Surpass Motor Vehicle Traffic Death Rates Among Adults 34 To 56

Adults between the ages of 34 and 56 are at a greater risk of dying from poisonings than from motor vehicle accidents, according to a new report from the CDC.

Adolescent Drinking Linked To Behavioural Problems

Teens who drink heavily are more likely than their peers to have behavioural and attention problems and suffer from anxiety and depression, a team led by researchers from the Norwegian University of Science and Technology (NTNU) has reported.

A New Software To Assess Driving Behaviour And Driving Risks

One of the aims imposed by the European Union in 2004 is to reduce the number of traffic accidents. However, despite the measures taken by the different administrations and the consequent decrease in the number of accidents, the results for 2010 are not close to those set by Europe. Gerardo Reveriego, a young researcher of the University of Mçˇlaga, has designed software that informs drivers of the risk situations s/he has while driving. This allows drivers to self-assess themselves and improve their driving behaviour.

GOP Senators Signal They Will Not Block Sotomayor; Full Senate Vote Expected By Aug. 7

Senate Republicans on Thursday said that they do not plan to block a vote on Supreme Court nominee Sonia Sotomayor, the Washington Post reports. Senate Judiciary Committee ranking member Jeff Sessions (R-Ala.) told Sotomayor that he would not support any effort to filibuster her nomination, meaning that she would need a simple majority of 50 votes to be confirmed. Because Democrats hold 60 votes in the Senate, Sessions" comments effectively end "any possible suspense over her fate," according to the Post (Kane et al., Washington Post, 7/17). Sessions said, "I will not support and I don"t think any member of this side will support a filibuster or any attempt to block a vote on your nomination," adding, "I look forward to you getting that vote before we recess in August." According to CQ Politics, Sessions" statement that Republicans will not filibuster "is bound to rile conservative activists," who have urged GOP senators to delay the vote to allow more time to build opposition.Sen. Lindsey Graham (R-S.C.) also signaled that he would vote for Sotomayor"s confirmation (Perine, CQ Politics, 7/16). He said, "We"ll see what your future holds, but I think it"s going to be pretty bright" (Bendavid, "Washington Wire," Wall Street Journal, 7/16). Sen. James Inhofe (R-Okla.) said that although he will not support Sotomayor"s confirmation, he will not filibuster the vote (Rushing, The Hill, 7/16). Sen. Tom Coburn (R-Okla.) told Sotomayor, "Thank you for giving us such a cordial response, and I am mightily impressed" (Washington Post, 7/17).Voting Timeline UnclearSenate Judiciary Committee Chair Patrick Leahy (D-Vt.) said he would schedule a committee vote on the nomination for July 21. It remains unclear whether committee Republicans will delay the vote until July 28, as they are permitted to do under committee rules. Sessions called the July 21 vote "unrealistic," adding that there "will be a number of questions submitted to the nominee that take some time" (CQ Politics, 7/16). A party-line vote on the nomination does not seem likely, as a number of committee Republicans have praised Sotomayor and signaled that they will vote to confirm her, the AP/Boston Globe reports (Holland, AP/Boston Globe, 7/17). The committee"s vote serves as a recommendation to the full Senate, which likely will hold its final roll-call vote on the nomination by Aug. 7 (Washington Post, 7/17). Senate Majority Leader Harry Reid (D-Nev.) on Thursday said he wants a floor vote on Sotomayor "as quickly as possible" (Brady, Roll Call, 7/16).During the hearing on Thursday, Sotomayor reiterated that she would consider each case individually and declined to state her specific views on abortion rights. In response to Coburn, she said, "Would you want a ... nominee who came in here and said, "I agree with you. This is unconstitutional," before I had a case before me?" She added, "I don"t know that that"s a justice that I can be" (Kiely/Biskupic, USA Today, 7/17). According to the New York Times, "Some observers thought they detected her tipping her hand on abortion rights when she said Supreme Court precedents required abortion restrictions to make exceptions for a woman"s health" (Savage, New York Times, 7/17).

House Approves Spending Bill Allowing D.C. To Use Locally Raised Funds For Abortion Services

The House on Thursday voted 219-208 to approve a fiscal year 2010 Financial Services spending bill (HR 3170), which includes a provision reversing a long-standing congressional ban on allowing Washington, D.C., to use locally derived revenue to fund or subsidize abortion services, the AP/Washington Post reports (AP/Washington Post, 7/17). The measure maintains a ban on using federal funds for abortion services in the district.According to CQ Today, Thursday"s vote followed a "lengthy and sometimes heated debate" marked by Republicans and some moderate Democrats" dissatisfaction with a rule restricting amendments. The House voted 216-213 to approve the rule, which allowed 17 amendments but excluded any on the D.C. abortion funding provision (Clarke, CQ Today, 7/16).

Daiichi Sankyo And MorphoSys Expand Collaboration With Two New Cancer-Related Antibody Programs

MorphoSys AG (Frankfurt Stock Exchange: MOR; Prime Standard Segment, TecDAX) announced the start of a further two oncology-focused therapeutic antibody programs within its collaboration with DAIICHI SANKYO COMPANY, LIMITED (TSE: 4568, hereinafter Daiichi Sankyo). By exercising two options available under the parties" existing agreement, Daiichi Sankyo has selected two new target molecules against which MorphoSys will generate antibodies using its proprietary HuCAL technology. Daiichi Sankyo will carry out pre-clinical and clinical development and has worldwide marketing rights for all resulting products. MorphoSys receives exclusive license fees and stands to receive milestones and royalties for the therapeutic antibody programs, as per the terms of the companies" existing agreement. Further financial details were not disclosed.

CBO: Health Reform Bills Bend Cost Curve In Wrong Direction

"Congress"s chief budget analyst delivered a devastating assessment yesterday of the health-care proposals drafted by congressional Democrats, fueling an insurrection among fiscal conservatives in the House and pushing negotiators in the Senate to redouble efforts to draw up a new plan that more effectively restrains federal spending," the Washington Post reports.

The Obama Administration Ramps Up Push For Health Care Reform

The Obama administration ramps up efforts to promote health care reform and reacts to a sobering announcement by the Congressional Budget Office about the scoring of a health care bill.

Mental Health Issues Among Veterans Increase Dramatically

A new study finds more veterans being diagnosed with mental health issues. The study was posted Thursday on the web site of The American Journal of Public Health.

A Selection Of Opinions And Editorials

Why The Cheers? The Washington Post

WHO Stops Tracking H1N1 Cases

"In a move that caught many public health experts by surprise, the WHO quietly announced Thursday that it would stop tracking swine flu cases and deaths around the world," the New York Times reports. According to the newspaper, the announcement "perplexed some experts, and even baffled a WHO spokesman, Gregory Hartl," who "earlier in the day ň€¦ had confirmed Argentina, with 137 swine flu deaths since June, had surpassed Mexico, where the epidemic began in February, as the country with second largest number of swine flu deaths." While the last WHO updated indicated nearly 95,000 people worldwide had been infected with H1N1, "[m]any epidemiologists have pointed out that, in reality, millions of people have had swine flu, usually in a mild form, so the numbers of laboratory-confirmed cases were actually meaningless" while tests "overwhelmed national laboratories," according to the New York Times (McNeil, 7/16).

Scientists Assess Flooding And Damage From 2008 Myanmar Cyclone - A Natural Disaster That Killed 138,000

Tropical cyclone Nargis made landfall in the Asian nation of Myanmar on May 2, 2008, causing the worst natural disaster in the country"s recorded history - with a death toll that may have exceeded 138,000. In the July 2009 issue of the journal Nature Geoscience, researchers report on a field survey done three months after the disaster to document the extent of the flooding and resulting damage.

TMA "Deeply Troubled" By Health Reform Bill

Texas Medical Association (TMA) statement from TMA president William H. Fleming III, MD, regarding H.R. 3200, "America"s Affordable Health Care Choices Act of 2009," Congressional legislation to reform America"s health care system.

Largest Lupus Drug Trial Ever Completed Is Successful!

Today, Human Genome Sciences (HGS) and GlaxoSmithKline (GSK) announced positive results from a year-long clinical trial of BENLYSTA for treating lupus. When the 52-week study concluded, the lupus patients who were treated with BENLYSTA had improvement in overall disease activity without clinically significant flare-ups in one or more isolated organs when compared to patients who received the placebo (inactive agent). The patients receiving BENLYSTA also were able to reduce their intake of steroid medications. The study is the largest ever to be completed for lupus and the first Phase III (late stage) trial of a new biologic immune therapy for lupus to succeed in meeting its primary endpoint and most of its secondary endpoints.

New Incentives Needed To Encourage GPs To Teach Medical Students, Australia

New strategies are needed to encourage general practitioners to teach medical students in their practices, according to a letter published in this year"s General Practice edition of the Medical Journal of Australia.

Gene Signature Helps Predict Breast Cancer Prognosis

Vanderbilt-Ingram Cancer Center researchers have uncovered a gene signature that may help predict clinical outcomes in certain types of breast cancer.

Johns Hopkins Faculty Members Awarded 2009 White House Early Career Awards

Pablo A. Celnik, M.D., an assistant professor of physical medicine and rehabilitation and neurology at the Johns Hopkins University School of Medicine, and Thao (Vicky) Nguyen, 32, assistant professor of mechanical engineering in the Whiting School of Engineering at The Johns Hopkins University, are among the 100 winners of this year"s Presidential Early Career Award for Scientists and Engineers (PECASE).

Risk Factors For Cardiovascular Disease Increasing In Younger Canadians Raise Concern About Future Rise In Heart Disease

The prevalence of heart disease and certain key risk factors - hypertension, diabetes, and obesity - are increasing in all age groups and most income groups in Canada found a new study published in CMAJ (Canadian Medical Association Journal) http://www.cmaj.ca/press/cmaj081629.pdf. This study, which looked at national data from 1994 to 2005, encompassed people aged 12 years and older sampling from Canadians of all socioeconomic and ethnic groups. Risk factors such as hypertension, diabetes, and obesity increased most rapidly among younger people between 12 to 50 years of age.

AARP Thanks Vice President Biden, Administration, For Working To Improve Health Care For Older Americans

This afternoon, AARP CEO A. Barry Rand delivered the following remarks at the White House Middle Class Task Force Town Hall in Alexandria, Va., during a discussion with Vice President Biden, Health and Human Services Secretary Kathleen Sebelius, and White House Office of Health Reform Director Nancy-Ann DeParle, on how health care reform will lower costs, cut waste, and improve quality for seniors from across the country.

La Jolla Institute Discovers Genetic Trigger For Disease-Fighting Antibodies

A research team led by the La Jolla Institute for Allergy & Immunology has identified the specific gene which triggers the body to produce disease-fighting antibodies -- a seminal finding that clarifies the exact molecular steps taken by the body to mount an antibody defense against viruses and other pathogens. The finding, published online in the prestigious journal Science, has major implications for the development of new and more effective vaccines. The La Jolla Institute"s Shane Crotty, Ph.D., was the lead scientist on the team, which also included researchers from Yale University.

AMA Supports H.R. 3200, "America\'s Affordable Health Choices Act Of 2009"

American Medical Association sent a letter to House leaders supporting H.R. 3200, "America"s Affordable Health Choices Act of 2009."

Researcher Awarded $1.6 Million To Investigate Tumor Suppressor\'s Role In Breast Cancer

Studies have estimated that five to

Perforomist Inhalation Solution Data Presented At American Thoracic Society Conference

Data from two presentations highlighting the use of Perforomist® (formoterol fumarate) Inhalation Solution in moderate to severe chronic obstructive pulmonary disease (COPD) patients were featured at the International Conference of the American Thoracic Society in San Diego. In one analysis, use of Perforomist Inhalation Solution, when added to maintenance tiotropium, resulted in improved pulmonary function, dyspnea (shortness of breath) and rescue medication use versus treatment with tiotropium alone. In a second study, patient satisfaction increased in those treated with Perforomist Inhalation Solution twice daily compared with ipratropium/albuterol metered-dose inhaler (MDI) four times daily.

Flu Symptoms Likely To Be Mild, Say Northern Ireland Doctors

Family doctors in Northern Ireland moved to allay fears over the swine flu virus.

No Change To Swine Flu Treatment Routes In Wales

Wales, along with the other devolved nations, will not be part of the National Pandemic Flu Service (NPFS) when it is launched next week in England, Health Minister Edwina Hart said today.

Northern California Cancer Center\'s First-of-Its-Kind Research Reveals Low Socioeconomic Status Often Equals Poor Chance Of Lymphoma Survival

The Northern California Cancer Center (NCCC) recently found that lower socioeconomic status is "significantly associated with substantially poorer survival" of follicular lymphoma in California.

Genetic Variation Associated With Survival Advantage In African Americans With HIV

From the start of the HIV epidemic, it appeared that some of the people who were infected with the virus were able to ward off the fatal effects of the disease longer than others. Recent studies have begun to unravel the cause of this phenomenon, and new research suggests that African Americans with the disease have a unique survival advantage if they have both a low white blood cell count (known as leukopenia) and a genetic variation that is found mainly in persons of African ancestry. This study was prepublished online on July 20, 2009, in Blood, the official journal of the American Society of Hematology.

Experts Support National Public Reporting Of Healthcare-Associated Infections

Five organizations representing the nation"s experts in infectious diseases medicine, infection prevention in healthcare settings, and public health and disease prevention announced their support for a provision requiring national reporting of healthcare-associated infection (HAI) rates, which is contained within the healthcare reform bill introduced by leaders of the U.S. House of Representatives.

Breast Cancer Drug Shows Promise Against Serious Infections

An FDA-approved drug used for preventing recurrence of breast cancer shows promise in fighting life-threatening fungal infections common in immune-compromised patients, such as infants born prematurely and patients with cancer. Some scientists suspected that tamoxifen has antifungal properties; now new research from the University of Rochester Medical Center shows that it actually kills fungus cells and stops them from causing disease.

The Sounds Of Learning: Studying The Impact Of Music On Children With Autism

In June 2009, newspapers reported that archaeologists in Germany had discovered a 35,000-year-old flute made of bird bone. It represented, one paper said, "the earliest known flowering of music-making in Stone Age culture." And we have been tapping our toes, humming along, singing and dancing ever since.

2009 World Stem Cell Summit Co-Sponsored By Johns Hopkins Medicine

WHAT: Johns Hopkins Medicine is co-sponsoring the 2009 World Stem Cell Summit to be held in Baltimore this September. http://www.worldstemcellsummit.com/index.html

Potential Problem-Solving In Transplant Operations From Genes That Let Creepy-Crawlies Survive A Deep Freeze

Arctic springtails (Megaphorura arctica) survive freezing temperatures by dehydrating themselves before the coldest weather sets in. Researchers writing in the open access journal BMC Genomics have identified a suite of genes involved in controlling this extreme survival mechanism.

Research In The Bolivian Rainforest Suggests Ancient, Shared Roots Of Feeding Behaviours In Monkeys And Humans

Behavioural ecologists working in Bolivia have found that wild spider monkeys control their diets in a similar way to humans, contrary to what has been thought up to now. Rather than trying to maximize their daily energy intake, the monkeys tightly regulate their daily protein intake, so that it stays at the same level regardless of seasonal variation in the availability of different foods.

Male Circumcision Does Not Appear To Reduce HIV Transmission Risk To Female Partners

Although several studies have shown that circumcision, removal of the foreskin which contains cells that are particularly susceptible to HIV, appears to reduce a man"s risk of contracting HIV from his female sex partner, it does not reduce the female sex partners" risk of contracting the virus, according to a study in the Lancet, Reuters reports. Maria Wawer of Johns Hopkins University and colleagues in Uganda followed 922 HIV-positive, uncircumcised men ages 15 to 49. Some of the men immediately underwent a circumcision, and some had the procedure two years later. The researchers also followed 163 female partners of the men.The researchers decided to end the study early when they found that male circumcision did not convey the expected benefits to women. The study also found that men"s partners were no less likely to contract other sexually transmitted infections, except for trichomonas.However, based on observational studies, researchers say that circumcision is so effective in protecting men that it will still likely benefit women indirectly by reducing circulation of the virus in general (Fox, Reuters, 7/16).